Marcel Tuppi

Oocyte DNA damage quality control requires consecutive interplay of CHK2 and CK1 to activate p63

Marcel Tuppi, Sebastian Kehrloesser, Daniel Coutandin et al. · Nature Structural & Molecular Biology · 2018 · 164 citations

Chromatin, Genome Instability, Dna Damage +13

Quality control in oocytes by p63 is based on a spring-loaded activation mechanism on the molecular and cellular level

Daniel Coutandin, Christian Osterburg, Ratnesh Kumar Srivastav et al. · eLife · 2016 · 70 citations · Full text

Oocyte, Molecular Regulation, Molecular Biology +26

Cell cycle arrest in mitosis promotes interferon-induced necroptosis

Tanja Frank, Marcel Tuppi, Manuela Hugle et al. · Cell Death and Differentiation · 2019 · 59 citations · Full text

Cell Division, Medicine, Apoptosis +7

The p63 C-terminus is essential for murine oocyte integrity

Anna Maria Lena, Valerio Rossi, Susanne Osterburg et al. · Nature Communications · 2021 · 58 citations · Full text

Intrinsic aggregation propensity of the p63 and p73 TI domains correlates with p53R175H interaction and suggests further significance of aggregation events in the p53 family

Sebastian Kehrloesser, Christian Osterburg, Marcel Tuppi et al. · Cell Death and Differentiation · 2016 · 57 citations · Full text

Aggregation Events, Medicine, Molecular Biology +7