Manuela Hugle

The dual PI3K/mTOR inhibitor NVP‐BEZ235 and chloroquine synergize to trigger apoptosis <i>via</i> mitochondrial‐lysosomal cross‐talk

Christian Seitz, Manuela Hugle, Silvia Cristofanon et al. · International Journal of Cancer · 2012 · 80 citations · Full text

Mitophagy, Apoptosis, Immunology +22

Pan-Mammalian Target of Rapamycin (mTOR) Inhibitor AZD8055 Primes Rhabdomyosarcoma Cells for ABT-737-induced Apoptosis by Down-regulating Mcl-1 Protein

Manuela Hugle, Romy Reimann, Marcel Schlecht et al. · Journal of Biological Chemistry · 2013 · 63 citations · Full text

Down-regulating Mcl-1 Protein, Pan-mammalian Target, Medicine +9

Cell cycle arrest in mitosis promotes interferon-induced necroptosis

Tanja Frank, Marcel Tuppi, Manuela Hugle et al. · Cell Death and Differentiation · 2019 · 59 citations · Full text

Cell Division, Medicine, Apoptosis +7

Identification of synthetic lethality of PLK1 inhibition and microtubule-destabilizing drugs

Manuela Hugle, Katharina Belz, Simone Fulda · Cell Death and Differentiation · 2015 · 56 citations · Full text

Drug Target, Biochemistry, Medicine +6

Synergistic induction of apoptosis by a polo‐like kinase 1 inhibitor and microtubule‐interfering drugs in <scp>E</scp>wing sarcoma cells

Lilly Magdalena Weiß, Manuela Hugle, Sarah Romero et al. · International Journal of Cancer · 2015 · 33 citations

Apoptosis, Cell Death, Pathology +20