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Apoptosis Threshold Set by Noxa and Mcl-1 after T Cell Activation Regulates Competitive Selection of High-Affinity Clones

Felix M. Wensveen, Klaas P. J. M. van Gisbergen, Ingrid A. M. Derks, Carmen Gerlach, Ton N. Schumacher, René A. W. van Lier, Eric Eldering

Immunity · 2010 · 91 citations · 47 references

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47

Noxa, a BH3-Only Member of the Bcl-2 Family and Candidate Mediator of p53-Induced Apoptosis

Eri Oda, Rieko Ohki, Hideki Murasawa et al. · Science · 2000 · 2.1K citations

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Inflammation Directs Memory Precursor and Short-Lived Effector CD8+ T Cell Fates via the Graded Expression of T-bet Transcription Factor

Nikhil S. Joshi, Weiguo Cui, Anmol Chandele et al. · Immunity · 2007 · 1.9K citations · Full text

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Differential Targeting of Prosurvival Bcl-2 Proteins by Their BH3-Only Ligands Allows Complementary Apoptotic Function

Lin Chen, Simon N. Willis, Andrew H. Wei et al. · Molecular Cell · 2005 · 1.8K citations · Full text

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Proapoptotic Bcl-2 Relative Bim Required for Certain Apoptotic Responses, Leukocyte Homeostasis, and to Preclude Autoimmunity

Philippe Bouillet, Donald Metcalf, David C.S. Huang et al. · Science · 1999 · 1.5K citations

, , +17

p53- and Drug-Induced Apoptotic Responses Mediated by BH3-Only Proteins Puma and Noxa

Andreas Villunger, Ewa M. Michalak, Leigh Coultas et al. · Science · 2003 · 1.3K citations

, , +17