Concepedia

Antibody Conjugates

Antibody Conjugates is a class of bioconjugated molecules in which a monoclonal antibody is covalently linked to a cytotoxic agent, radionuclide, or other functional moiety to enable targeted delivery to specific antigens expressed on diseased cells.

5K

Publications

268.6K

Citations

22.7K

Authors

3.6K

Institutions

Publications per year

2017–2026

1.6K

Parents

Children

Publications

5K

PEROXIDASE-LABELED ANTIBODY A NEW METHOD OF CONJUGATION

Paul K. Nakane, Akira Kawaoi · Journal of Histochemistry & Cytochemistry · 1974 · 2.4K citations · Full text

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A rapid, sensitive method for detection of alkaline phosphatase-conjugated anti-antibody on Western blots

M. S. Blake, Kenneth H. Johnston, G.J. Russell-Jones et al. · Analytical Biochemistry · 1984 · 2.1K citations

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Targeting HER2-Positive Breast Cancer with Trastuzumab-DM1, an Antibody–Cytotoxic Drug Conjugate

Gail D. Lewis Phillips, Guangmin Li, Debra L. Dugger et al. · Cancer Research · 2008 · 1.7K citations

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Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index

Jagath R. Junutula, Helga Raab, Suzanna Clark et al. · Nature Biotechnology · 2008 · 1.4K citations

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Effects of Drug Loading on the Antitumor Activity of a Monoclonal Antibody Drug Conjugate

Kevin J. Hamblett, Peter D. Senter, Dana F. Chace et al. · Clinical Cancer Research · 2004 · 1.2K citations

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1–5 of 5K

Authors

22.7K

  1. PD
    Peter D. Senter

    Seagen (United States), United States

    45 publications · 9.4K citations

    31

    h-index

  2. DM
    David M. Goldenberg

    Center for Molecular Medicine and Immunology, United States

    40 publications · 3.6K citations

    30

    h-index

  3. SY
    Shang‐Fan Yu

    WuXi AppTec (China), China

    38 publications · 4K citations

    30

    h-index

  4. KR
    Katherine R. Kozak

    WuXi AppTec (China), China

    35 publications · 2.5K citations

    27

    h-index

  5. JM
    John M. Lambert

    ImmunoGen (United States), United States

    29 publications · 4.7K citations

    26

    h-index

1–5 of 22.7K

Institutions

3.6K

  1. Seagen (United States)

    Bothell, United States

    49 h-index

    668 publications

    125.4K citations

  2. National Cancer Institute

    Bethesda, United States

    48 h-index

    405 publications

    24.9K citations

  3. National Institutes of Health

    Bethesda, United States

    47 h-index

    489 publications

    29.7K citations

  4. Memorial Sloan Kettering Cancer Center

    New York, United States

    43 h-index

    282 publications

    22.3K citations

  5. Harvard University

    Cambridge, United States

    42 h-index

    313 publications

    19K citations

  6. Pfizer (United States)

    New York, United States

    39 h-index

    626 publications

    39K citations

  7. University College London

    London, United Kingdom

    39 h-index

    273 publications

    19.9K citations

  8. Centre National de la Recherche Scientifique

    Paris, France

    38 h-index

    391 publications

    16.9K citations

1–8 of 3.6K

Venues

  1. Bioconjugate Chemistry

    409 publications · 25.3K citations

    79

    h-index

  2. PubMed

    Repository · 330 publications · 16K citations

    64

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 75 publications · 8.8K citations

    54

    h-index

  4. Molecular Cancer Therapeutics

    MCT · 107 publications · 7.5K citations

    52

    h-index

  5. Journal of the American Chemical Society

    JACS · 51 publications · 4.7K citations

    41

    h-index

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