ARNT-Deficient Mice and Placental Differentiation

Katherine R. Kozak, Barbara D. Abbott, Oliver Hankinson

Developmental Biology

Knockout MouseDevelopmental BiologyPlacental DevelopmentGeneticsArnt-deficient Mice +4

Characterization of serum biomarkers for detection of early stage ovarian cancer

Katherine R. Kozak, Feng Su, Julian P. Whitelegge, +3

PROTEOMICS

Biomarker (Medicine)Prognostic BiomarkersOncologyEngineeringCancer Detection +12

Identification of biomarkers for ovarian cancer using strong anion-exchange ProteinChips: Potential use in diagnosis and prognosis

Katherine R. Kozak, M. Amneus, Suzanne M. Pusey, +5

Proceedings of the National Academy of Sciences

Impact of Drug Conjugation on Pharmacokinetics and Tissue Distribution of Anti-STEAP1 Antibody–Drug Conjugates in Rats

C. Andrew Boswell, Eduardo E. Mundo, Crystal Zhang, +16

Bioconjugate Chemistry

NanotherapeuticsLocal PharmacologyImmunologyCellular PharmacologyPharmacotherapy +21

Galectin-1 Specifically Modulates TCR Signals to Enhance TCR Apoptosis but Inhibit IL-2 Production and Proliferation

G N R Vespa, Linda A. Lewis, Katherine R. Kozak, +4

The Journal of Immunology

T-regulatory CellImmune RegulationImmunologyCell DeathImmunologic Mechanism +16

Antibody Conjugation of a Chimeric BET Degrader Enables <i>in vivo</i> Activity

Thomas H. Pillow, Pragya Adhikari, Robert A. Blake, +29

ChemMedChem

Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy

Peter S. Dragovich, Thomas H. Pillow, Robert A. Blake, +34

Journal of Medicinal Chemistry

Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody–drug conjugates

Leanna R. Staben, Stefan G. Koenig, Sophie M. Lehar, +20

Nature Chemistry

Medicinal ChemistryAntibody–drug ConjugatesDrug TargetingMedicineTargeted Drug Delivery +6

Cathepsin B Is Dispensable for Cellular Processing of Cathepsin B-Cleavable Antibody–Drug Conjugates

Niña G. Caculitan, Josefa Chuh, Yong Ma, +12

Cancer Research

Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 1: Exploration of Antibody Linker, Payload Loading, and Payload Molecular Properties

Peter S. Dragovich, Thomas H. Pillow, Robert A. Blake, +34

Journal of Medicinal Chemistry