John M. Lambert

Targeting HER2-Positive Breast Cancer with Trastuzumab-DM1, an Antibody–Cytotoxic Drug Conjugate

Gail D. Lewis Phillips, Guangmin Li, Debra L. Dugger et al. · Cancer Research · 2008 · 1.7K citations

Pharmacy, Oncology, Pharmacology +17

Ado-trastuzumab Emtansine (T-DM1): An Antibody–Drug Conjugate (ADC) for HER2-Positive Breast Cancer

John M. Lambert, Ravi Chari · Journal of Medicinal Chemistry · 2014 · 532 citations

Medicine, Oncology, Pharmacology +17

Structural characterization of the maytansinoid–monoclonal antibody immunoconjugate, huN901–DM1, by mass spectrometry

Lintao Wang, Godfrey Amphlett, Walter A. Blättler et al. · Protein Science · 2005 · 368 citations · Full text

Pharmacy, Oncology, Pharmacology +17

Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism

John M. Lambert, Que T. Lambert, Gary W. Reuther et al. · Nature Cell Biology · 2002 · 326 citations

Life Sciences, Cell Biology, Molecular Biology +11

Effects of Drug–Antibody Ratio on Pharmacokinetics, Biodistribution, Efficacy, and Tolerability of Antibody–Maytansinoid Conjugates

Xiuxia Sun, Jose F. Ponte, Nicholas C. Yoder et al. · Bioconjugate Chemistry · 2017 · 253 citations

Pharmacy, Oncology, Pharmacology +17