Affinity Improvement is a methodological advancement in immunology that refers to the incremental enhancement of antibody-antigen binding strength through somatic hypermutation and selective pressure during the maturation of B cells in germinal centers.
243
Publications
12.5K
Citations
1.6K
Authors
495
Institutions
Publications per year
2017–2026
69
Parents
Publications
243
Michael Hudecek, Maria Teresa Lupo Stanghellini, Paula L. Kosasih et al. · Clinical Cancer Research · 2013 · 540 citations · Full text
Life Sciences, Immunology, Oncology +17
Design and Use of a Phage Display Library
Alessandro Pini, Francesca Viti, Annalisa Santucci et al. · Journal of Biological Chemistry · 1998 · 423 citations · Full text
1–5 of 243
Authors
1.6K
- KD
3
h-index
- KT
3
h-index
- MD
3
h-index
- IP
3
h-index
- MN
3
h-index
1–5 of 1.6K
Institutions
495
National Institutes of Health
Bethesda, United States
13 h-index
47 publications
4.1K citations
Scripps Research Institute
San Diego, United States
11 h-index
41 publications
6.4K citations
National Cancer Institute
Bethesda, United States
9 h-index
29 publications
3K citations
Centre National de la Recherche Scientifique
Paris, France
7 h-index
34 publications
2K citations
Inserm
Paris, France
6 h-index
19 publications
1.4K citations
Massachusetts Institute of Technology
Cambridge, United States
5 h-index
16 publications
1.3K citations
The University of Tokyo
Tokyo, Japan
5 h-index
26 publications
1.4K citations
Technical University of Munich
Munich, Germany
4 h-index
17 publications
4.2K citations
1–8 of 495
Venues
- Journal of Medicinal Chemistry
18 publications · 729 citations
17
h-index
- Proceedings of the National Academy of Sciences
PNAS · 11 publications · 1.2K citations
11
h-index
- Protein Engineering Design and Selection
PEDS · 10 publications · 639 citations
10
h-index
- The Journal of Immunology
JI · 10 publications · 478 citations
10
h-index
- Journal of the American Chemical Society
JACS · 8 publications · 491 citations
8
h-index
1–5