Che‐Wah Lee

Discovery of the Potent and Selective M1 PAM-Agonist<i>N</i>-[(3<i>R</i>,4<i>S</i>)-3-Hydroxytetrahydro-2<i>H</i>-pyran-4-yl]-5-methyl-4-[4-(1,3-thiazol-4-yl)benzyl]pyridine-2-carboxamide (PF-06767832): Evaluation of Efficacy and Cholinergic Side Effects

Jennifer E. Davoren, Che‐Wah Lee, Michelle R. Garnsey et al. · Journal of Medicinal Chemistry · 2016 · 83 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Design and optimization of selective azaindole amide M1 positive allosteric modulators

Jennifer E. Davoren, Steven V. O’Neil, Dennis P. Anderson et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 44 citations · Full text

Pharmacy, Medicinal Chemistry, Drug Design +13

The Discovery of a Novel Phosphodiesterase (PDE) 4B-Preferring Radioligand for Positron Emission Tomography (PET) Imaging

Lei Zhang, Laigao Chen, Elizabeth M. Beck et al. · Journal of Medicinal Chemistry · 2017 · 36 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Application of Structure-Based Design and Parallel Chemistry to Identify a Potent, Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor

Christopher J. Helal, Eric P. Arnold, Tracey Boyden et al. · Journal of Medicinal Chemistry · 2017 · 32 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Direct and catalyzed electrochemical syntheses in microemulsions

Hermes Carrero, Jianxin Gao, James F. Rusling et al. · Electrochimica Acta · 1999 · 30 citations

Natural Sciences, Chemical Engineering, Chemistry +12