Steven V. O’Neil - Concepedia

Author

Steven V. O’Neil

Also Known As

O'Neil, S.V., S. O'neil, S. V. O'NEIL, S.V. O'Neil, Shannon O'Neil, Steven O’Neil, Steven V O'Neil, Steven V. O'Neil, Steven V. O’Neil

Publications

858

Citations

H-Index

Concepts

All Affiliations

Pfizer (United States)Procter & Gamble (United States)Brandeis University University of North Carolina at Chapel Hill The Ohio State University

About

Steven V. O’Neil is an author at Pfizer (United States) specializing in natural sciences, pharmacology, and biochemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Natural Sciences	13	15	352
2	Biochemistry	12	14	366
3	Medicine	11	11	400
4	Engineering	6	6	136
5	Social Sciences	2	2	131

Steven V. O’Neil

Publications

797

Citations

H-Index

Page 1

	Year	Citations
Negative allosteric modulation of metabotropic glutamate receptor 5 results in broad spectrum activity relevant to treatment resistant depression Zoë A. Hughes, Sarah J. Neal Webb, Daniel L. Smith, Neuropharmacology PsychiatryNegative Allosteric ModulationTreatment Resistant DepressionMedicineNeurotransmitter	2012	85
Discovery of the Potent and Selective M1 PAM-Agonist<i>N</i>-[(3<i>R</i>,4<i>S</i>)-3-Hydroxytetrahydro-2<i>H</i>-pyran-4-yl]-5-methyl-4-[4-(1,3-thiazol-4-yl)benzyl]pyridine-2-carboxamide (PF-06767832): Evaluation of Efficacy and Cholinergic Side Effects Jennifer E. Davoren, Che‐Wah Lee, Michelle R. Garnsey, Journal of Medicinal Chemistry	2016	83
Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation Laura A. McAllister, Christopher R. Butler, Scot Mente, Journal of Medicinal Chemistry Chemical BiologyMedicinal ChemistryPharmaceutical ScienceCompound 15Biochemistry	2018	78
Design and Synthesis of γ- and δ-Lactam M<sub>1</sub> Positive Allosteric Modulators (PAMs): Convulsion and Cholinergic Toxicity of an M<sub>1</sub>-Selective PAM with Weak Agonist Activity Jennifer E. Davoren, Michelle R. Garnsey, Betty Pettersen, Journal of Medicinal Chemistry	2017	58
Design and synthesis of novel N-sulfonyl-2-indole carboxamides as potent PPAR-γ binding agents with potential application to the treatment of osteoporosis Corey R. Hopkins, Steven V. O’Neil, Michael C. Laufersweiler, Bioorganic & Medicinal Chemistry Letters BiochemistryMedicinePotential ApplicationNovel N-sulfonyl-2-indole CarboxamidesPharmacological Agent	2006	49
Sensorimotor impairment and elevated levels of dopamine metabolites in the neostriatum occur rapidly after intranigral injection of 6-hydroxydopamine or gamma-hydroxybutyrate in awake rats C. Anthony Altar, Steven V. O’Neil, John F. Marshall Neuropharmacology Awake RatsNeuropsychologyPsychoactive DrugNeurophysiologyNeuroanatomy	1984	46
Design and optimization of selective azaindole amide M1 positive allosteric modulators Jennifer E. Davoren, Steven V. O’Neil, Dennis P. Anderson, Bioorganic & Medicinal Chemistry Letters	2015	44
Synthesis and biological activity of 5-aryl-4-(4-(5-methyl-1H-imidazol-4-yl)piperidin-1-yl)pyrimidine analogs as potent, highly selective, and orally bioavailable NHE-1 inhibitors Karnail S. Atwal, Steven V. O’Neil, Saleem Ahmad, Bioorganic & Medicinal Chemistry Letters Biological ActivityBioavailable Nhe-1 InhibitorsMedicinal ChemistryPyrimidine AnalogsBiochemistry	2006	41
Synthesis of (±)-Allocyathin B<sub>2</sub> and (+)-Erinacine A Barry B. Snider, Nha Huu Vo, Steven V. O’Neil The Journal of Organic Chemistry Bioorganic ChemistryAllocyathin B2BiochemistryEngineeringNatural Sciences	1998	37
Identification and Development of an Irreversible Monoacylglycerol Lipase (MAGL) Positron Emission Tomography (PET) Radioligand with High Specificity Lei Zhang, Christopher R. Butler, Kevin Maresca, Journal of Medicinal Chemistry	2019	33

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