Michael C. Laufersweiler

Correlation of chemical structure with reproductive and developmental toxicity as it relates to the use of the threshold of toxicological concern

Michael C. Laufersweiler, Bernard Gadagbui, Irene Abraham et al. · Regulatory Toxicology and Pharmacology · 2011 · 1.6K citations

Infertility, Developmental Biology, Fertility +14

Framework for Identifying Chemicals with Structural Features Associated with the Potential to Act as Developmental or Reproductive Toxicants

Shengde Wu, Joan Fisher, Jorge M. Naciff et al. · Chemical Research in Toxicology · 2013 · 178 citations

Potent and Selective Carboxylic Acid-Based Inhibitors of Matrix Metalloproteinases

Stanisław Pikul, Norman E. Ohler, Greg Ciszewski et al. · Journal of Medicinal Chemistry · 2001 · 51 citations · Full text

Substituted Piperidine, Medicinal Chemistry, Bioorganic Chemistry +12

Design and synthesis of novel N-sulfonyl-2-indole carboxamides as potent PPAR-γ binding agents with potential application to the treatment of osteoporosis

Corey R. Hopkins, Steven V. O’Neil, Michael C. Laufersweiler et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 49 citations · Full text

Biochemistry, Medicine, Potential Application +7

Bolstering the existing database supporting the non-cancer Threshold of Toxicological Concern values with toxicity data on fragrance-related materials

Atish Patel, Kaushal Joshi, Jane Rose et al. · Regulatory Toxicology and Pharmacology · 2020 · 35 citations · Full text

Non-cancer Threshold, Exposure Assessment, Ttc Dataset +22