Eric P. Arnold

Varenicline:  An α4β2 Nicotinic Receptor Partial Agonist for Smoking Cessation

Jotham W. Coe, Paige R. Brooks, Michael G. Vetelino et al. · Journal of Medicinal Chemistry · 2005 · 929 citations · Full text

Dual Inhibition of TYK2 and JAK1 for the Treatment of Autoimmune Diseases: Discovery of (( <i>S</i> )-2,2-Difluorocyclopropyl)((1 <i>R</i> ,5 <i>S</i> )-3-(2-((1-methyl-1 <i>H</i> -pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone (PF-06700841)

Andrew Fensome, Catherine M. Ambler, Eric P. Arnold et al. · Journal of Medicinal Chemistry · 2018 · 165 citations · Full text

Identification of <i>N</i>-{<i>cis</i>-3-[Methyl(7<i>H</i>-pyrrolo[2,3-<i>d</i>]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases

Michael L. Vazquez, Neelu Kaila, Joseph W. Strohbach et al. · Journal of Medicinal Chemistry · 2018 · 160 citations · Full text

Immunodeficiencies, Janus Kinases, Immunology +22

Total Synthesis of (±)-Cytisine

Brian T. O’Neill, Daniel Yohannes, Mark W. Bundesmann et al. · Organic Letters · 2000 · 89 citations

Molecular Pharmacology, Derivative (Chemistry), Derivatives +12

3,5-Bicyclic aryl piperidines: A novel class of α4β2 neuronal nicotinic receptor partial agonists for smoking cessation

Jotham W. Coe, Paige R. Brooks, Michael Wirtz et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 73 citations · Full text

Tobacco Cessation, Tobacco Control, Molecular Pharmacology +11