Christopher J. Helal

A platform for automated nanomole-scale reaction screening and micromole-scale synthesis in flow

Damith Perera, Joseph W. Tucker, Shalini Brahmbhatt et al. · Science · 2018 · 489 citations

Pharmacy, Chemical Engineering, Chemistry +17

Design and Selection Parameters to Accelerate the Discovery of Novel Central Nervous System Positron Emission Tomography (PET) Ligands and Their Application in the Development of a Novel Phosphodiesterase 2A PET Ligand

Lei Zhang, Anabella Villalobos, Elizabeth M. Beck et al. · Journal of Medicinal Chemistry · 2013 · 203 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Novel electronic effects of remote substituents on the oxazaborolidine-catalyzed enantioselective reduction of ketones

E. J. Corey, Christopher J. Helal · Tetrahedron Letters · 1995 · 157 citations

Natural Sciences, Chemistry, Medicinal Chemistry +16

Direct Catalytic Enantioselective Reduction of Achiral α,β-Ynones. Strong Remote Steric Effects Across the C−C Triple Bond

Christopher J. Helal, Plato Α. Magriotis, E. J. Corey · Journal of the American Chemical Society · 1996 · 145 citations

Natural Sciences, Chemical Biology, Chemistry +9

Introduction of a Crystalline, Shelf-Stable Reagent for the Synthesis of Sulfur(VI) Fluorides

Hua Zhou, Paramita Mukherjee, Rongqiang Liu et al. · Organic Letters · 2018 · 140 citations

Natural Sciences, Chemical Engineering, Chemistry +8