Anabella Villalobos

Moving beyond Rules: The Development of a Central Nervous System Multiparameter Optimization (CNS MPO) Approach To Enable Alignment of Druglike Properties

Travis T. Wager, Xinjun Hou, Patrick R. Verhoest et al. · ACS Chemical Neuroscience · 2010 · 1K citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Central Nervous System Multiparameter Optimization Desirability: Application in Drug Discovery

Travis T. Wager, Xinjun Hou, Patrick R. Verhoest et al. · ACS Chemical Neuroscience · 2016 · 605 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Defining Desirable Central Nervous System Drug Space through the Alignment of Molecular Properties, in Vitro ADME, and Safety Attributes

Travis T. Wager, Ramalakshmi Y. Chandrasekaran, Xinjun Hou et al. · ACS Chemical Neuroscience · 2010 · 483 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Design and Selection Parameters to Accelerate the Discovery of Novel Central Nervous System Positron Emission Tomography (PET) Ligands and Their Application in the Development of a Novel Phosphodiesterase 2A PET Ligand

Lei Zhang, Anabella Villalobos, Elizabeth M. Beck et al. · Journal of Medicinal Chemistry · 2013 · 203 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Pharmacology of selective acetylcholinesterase inhibitors: implications for use in Alzheimer's disease

Dane Liston, Jann A. Nielsen, Anabella Villalobos et al. · European Journal of Pharmacology · 2003 · 192 citations

Life Sciences, Neuroscience, Pharmacology +12