Nickolay Y. Chirgadze

Viracept (Nelfinavir Mesylate, AG1343):  A Potent, Orally Bioavailable Inhibitor of HIV-1 Protease

Stephen W. Kaldor, Vincent J. Kalish, Jay F. Davies et al. · Journal of Medicinal Chemistry · 1997 · 617 citations · Full text

Immunology, Antiviral Drug, Nelfinavir Mesylate +17

Structure-based design of the first potent and selective inhibitor of human non-pancreatic secretory phospholipase A2

Richard W. Schevitz, Nicholas J. Bach, D. G. CARLSON et al. · Nature Structural & Molecular Biology · 1995 · 214 citations · Full text

Proteinlipid Interaction, Biochemistry, G Protein-coupled Receptor +8

Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases

A.U. Singer, John R. Rohde, Robert Lam et al. · Nature Structural & Molecular Biology · 2008 · 157 citations · Full text

Molecular Biology, New Class, E3 Ubiquitin Ligases +3

The Discovery of Polo-Like Kinase 4 Inhibitors: Design and Optimization of Spiro[cyclopropane-1,3′[3<i>H</i>]indol]-2′(1′<i>H</i>)-ones as Orally Bioavailable Antitumor Agents

Peter B. Sampson, Yong Liu, Narendra Kumar Patel et al. · Journal of Medicinal Chemistry · 2014 · 109 citations

Pharmaceutical Science, Polo-like Kinase Family, Compound 18 +22

Crystal Structure of Human Parathyroid Hormone 1–34 at 0.9-Å Resolution

Lei Jin, Srinivasan Chandrasekhar, Nickolay Y. Chirgadze et al. · Journal of Biological Chemistry · 2000 · 109 citations · Full text