Nicholas J. Bach

Essential features of the P-glycoprotein pharmacophore as defined by a series of reserpine analogs that modulate multidrug resistance.

Homer L. Pearce, Ahmad R. Safa, Nicholas J. Bach et al. · Proceedings of the National Academy of Sciences · 1989 · 234 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Structure-based design of the first potent and selective inhibitor of human non-pancreatic secretory phospholipase A2

Richard W. Schevitz, Nicholas J. Bach, D. G. CARLSON et al. · Nature Structural & Molecular Biology · 1995 · 215 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Bicyclic and tricyclic ergoline partial structures. Rigid 3-(2-aminoethyl)pyrroles and 3- and 4-(2-aminoethyl)pyrazoles as dopamine agonists

Nicholas J. Bach, Edmund C. Kornfeld, Noel D. Jones et al. · Journal of Medicinal Chemistry · 1980 · 170 citations

Medicine, Medicinal Chemistry, Pharmacology +15

Effects of (8β)-8-[(Methylthio)methyl]-6-propylergoline on dopaminergic function and brain dopamine turnover in rats

Ray W. Fuller, James A. Clemens, Edmund C. Kornfeld et al. · Life Sciences · 1979 · 104 citations

Medicine, Neuroscience, Pharmacology +13

Indole Inhibitors of Human Nonpancreatic Secretory Phospholipase A₂. 3. Indole-3-glyoxamides

Susan E. Draheim, Nicholas J. Bach, Robert D. Dillard et al. · Journal of Medicinal Chemistry · 1996 · 91 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10