Jay F. Davies - Concepedia

Concepedia

Author

Jay F. Davies

General Atomics (United States)

Also Known As

Davies, Jay, J F Davies, J. F. II DAVIES, J.F. Davies, J.F. Davies /II, J.F. Davies II, Jay Davies, Jay F. Davies

28

Publications

2.5K

Citations

16

H-Index

31

Concepts

All Affiliations

General Atomics (United States)Agouron Institute Pfizer (United States)University of California San Diego Southern Research Institute

JF

About

Jay F. Davies is an author at General Atomics (United States) specializing in biochemistry, natural sciences, and medicine.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	10	10	987
2	Natural Sciences	10	10	1.1K
3	Biochemistry	10	10	1.1K
4	Biomolecular Engineering	1	1	12
5	Cellular Physiology	1	1	31

Jay F. Davies

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17

Publications

2.5K

Citations

16

H-Index

	Year	Citations
Viracept (Nelfinavir Mesylate, AG1343): A Potent, Orally Bioavailable Inhibitor of HIV-1 Protease Stephen W. Kaldor, Vincent J. Kalish, Jay F. Davies, Journal of Medicinal Chemistry ImmunologyAntiviral DrugNelfinavir MesylateMedicinal ChemistryHiv-1 Protease	1997	617
Crystal Structure of the Ribonuclease H Domain of HIV-1 Reverse Transcriptase Jay F. Davies, Zuzana Hostomska, Zdeněk Hostomský, Science	1991	566
Discovery of Ketone-Based Covalent Inhibitors of Coronavirus 3CL Proteases for the Potential Therapeutic Treatment of COVID-19 Robert L. Hoffman, Robert S. Kania, Mary A. Brothers, Journal of Medicinal Chemistry	2020	518
Crystal structures of recombinant human dihydrofolate reductase complexed with folate and 5-deazafolate Jay F. Davies, Tavner J. Delcamp, Neal J. Prendergast, Biochemistry	1990	179
2.3 Å crystal structure of the catalytic domain of DNA polymerase β Jay F. Davies, Robert J. Almassy, Zuzana Hostomska, Cell Catalytic DomainNucleic Acid Chemistryå Crystal StructureBiochemistryNatural Sciences	1994	168
Dihydroxyphenylisoindoline Amides as Orally Bioavailable Inhibitors of the Heat Shock Protein 90 (Hsp90) Molecular Chaperone Pei‐Pei Kung, Buwen Huang, Gang Zhang, Journal of Medicinal Chemistry Pharmaceutical ScienceChemical BiologyPharmaceutical ChemistryMedicinal ChemistryChaperones	2009	73
Crystal structure of chicken liver dihydrofolate reductase complexed with NADP+ and biopterin Michele McTigue, Jay F. Davies, Bernard T. Kaufman, Biochemistry Chemical BiologyCrystal StructureAldehyde DehydrogenaseAldo-keto ReductaseBiochemistry	1992	70
Dihydroxylphenyl amides as inhibitors of the Hsp90 molecular chaperone Pei‐Pei Kung, Lee Funk, Jerry Meng, Bioorganic & Medicinal Chemistry Letters BiochemistryNatural SciencesMedicineRational Drug DesignChaperones	2008	52
Protein structure-based design of potent orally bioavailable, nonpeptide inhibitors of human immunodeficiency virus protease. Siegfried Reich, Michael Melnick, Jay F. Davies, Proceedings of the National Academy of Sciences Molecular BiologyProtein Structure-based DesignAntiviral DrugLead CompoundMedicinal Chemistry	1995	51
Structure-Based Design and Synthesis of Substituted 2-Butanols as Nonpeptidic Inhibitors of HIV Protease: Secondary Amide Series Siegfried Reich, Michael Melnick, Mark J. Pino, Journal of Medicinal Chemistry	1996	43

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