Concepedia

Jay F. Davies

JF

17

Publications

2.5K

Citations

16

H-Index

1990

Active since

Affiliations

General Atomics (United States)(Current)

Agouron Institute

Pfizer (United States)

University of California San Diego

Southern Research Institute

Jay F. Davies is an author at General Atomics (United States) specializing in biochemistry, natural sciences, and medicine.

Top concepts

MedicineBiochemistryNatural SciencesDrug DiscoveryMolecular BiologyStructural BiologyPharmacologyHivChemical BiologyMedicinal Chemistry

Publications per year

1990–2020

17

Publications

17

Viracept (Nelfinavir Mesylate, AG1343): A Potent, Orally Bioavailable Inhibitor of HIV-1 Protease

Stephen W. Kaldor, Vincent J. Kalish, Jay F. Davies et al. · Journal of Medicinal Chemistry · 1997 · 617 citations · Full text

Immunology, Antiviral Drug, Nelfinavir Mesylate +17

Crystal Structure of the Ribonuclease H Domain of HIV-1 Reverse Transcriptase

Jay F. Davies, Zuzana Hostomska, Zdeněk Hostomský et al. · Science · 1991 · 566 citations

Discovery of Ketone-Based Covalent Inhibitors of Coronavirus 3CL Proteases for the Potential Therapeutic Treatment of COVID-19

Robert L. Hoffman, Robert S. Kania, Mary A. Brothers et al. · Journal of Medicinal Chemistry · 2020 · 518 citations · Full text

Crystal structures of recombinant human dihydrofolate reductase complexed with folate and 5-deazafolate

Jay F. Davies, Tavner J. Delcamp, Neal J. Prendergast et al. · Biochemistry · 1990 · 179 citations

2.3 Å crystal structure of the catalytic domain of DNA polymerase β

Jay F. Davies, Robert J. Almassy, Zuzana Hostomska et al. · Cell · 1994 · 168 citations

Catalytic Domain, Nucleic Acid Chemistry, å Crystal Structure +9

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