Peter B. Sampson

The Discovery of Polo-Like Kinase 4 Inhibitors: Identification of (1<i>R</i>,2<i>S</i>)-2-(3-((<i>E</i>)-4-(((<i>cis</i>)-2,6-Dimethylmorpholino)methyl)styryl)-1<i>H</i>-indazol-6-yl)-5′-methoxyspiro[cyclopropane-1,3′-indolin]-2′-one (CFI-400945) as a Potent, Orally Active Antitumor Agent

Peter B. Sampson, Yong Liu, Bryan Forrest et al. · Journal of Medicinal Chemistry · 2014 · 166 citations · Full text

The Discovery of Polo-Like Kinase 4 Inhibitors: Design and Optimization of Spiro[cyclopropane-1,3′[3<i>H</i>]indol]-2′(1′<i>H</i>)-ones as Orally Bioavailable Antitumor Agents

Peter B. Sampson, Yong Liu, Narendra Kumar Patel et al. · Journal of Medicinal Chemistry · 2014 · 109 citations

Pharmaceutical Science, Polo-like Kinase Family, Compound 18 +22

Insights into the Mechanism of <i>Escherichia coli</i> Methionine Aminopeptidase from the Structural Analysis of Reaction Products and Phosphorus-Based Transition-State Analogues^,

W. Todd Lowther, Yan Zhang, Peter B. Sampson et al. · Biochemistry · 1999 · 102 citations

Discovery of Pyrazolo[1,5-<i>a</i>]pyrimidine TTK Inhibitors: CFI-402257 is a Potent, Selective, Bioavailable Anticancer Agent

Yong Liu, Radoslaw S. Laufer, Narendra Kumar Patel et al. · ACS Medicinal Chemistry Letters · 2016 · 78 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Drug Target +14

Use of Analogues of Methionine and Methionyl Adenylate to Sample Conformational Changes During Catalysis in Escherichia coli Methionyl-tRNA Synthetase

Thibaut Crépin, Emmanuelle Schmitt, Yves Méchulam et al. · Journal of Molecular Biology · 2003 · 75 citations

Biosynthesis, Sample Conformational Changes, Biochemistry +8