Steve Tam

Indole Cytosolic Phospholipase A₂α Inhibitors: Discovery and in Vitro and in Vivo Characterization of 4-{3-[5-Chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1<i>H</i>-indol-3-yl]propyl}benzoic Acid, Efipladib

John C. McKew, Katherine L. Lee, Marina W. H. Shen et al. · Journal of Medicinal Chemistry · 2008 · 88 citations

Inhibition of Cytosolic Phospholipase A₂α: Hit to Lead Optimization

John C. McKew, Megan A. Foley, Paresh Thakker et al. · Journal of Medicinal Chemistry · 2005 · 76 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Inhibitory Activity +13

Structure–activity studies of a series of dipyrazolo[3,4-b:3′,4′-d]pyridin-3-ones binding to the immune regulatory protein B7.1

Neal J. Green, Jason Xiang, Jing Chen et al. · Bioorganic & Medicinal Chemistry · 2003 · 44 citations

Benzhydrylquinazolinediones: Novel cytosolic phospholipase A2α inhibitors with improved physicochemical properties

Steven J. Kirincich, Jason Xiang, Neal Green et al. · Bioorganic & Medicinal Chemistry · 2009 · 31 citations

Molecular Pharmacology, Medicinal Chemistry, Improved Physicochemical Properties +12

Potential therapeutic uses of phospholipase A₂inhibitors

James D. Clark, Steve Tam · Expert Opinion on Therapeutic Patents · 2004 · 29 citations

Inflammatory Lung Disease, Immunology, Cell Death +18