Marina W. H. Shen

Cytosolic phospholipase A2α–deficient mice are resistant to experimental autoimmune encephalomyelitis

Suzana Marušić, Michael W. Leach, Jeffrey W. Pelker et al. · The Journal of Experimental Medicine · 2005 · 146 citations · Full text

Discovery of Clinical Candidate 1-{[(2 <i>S</i> ,3 <i>S</i> ,4 <i>S</i> )-3-Ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide (PF-06650833), a Potent, Selective Inhibitor of Interleukin-1 Receptor Associated Kinase 4 (IRAK4), by Fragment-Based Drug Design

Katherine L. Lee, Catherine M. Ambler, David R. Anderson et al. · Journal of Medicinal Chemistry · 2017 · 138 citations · Full text

Indole Cytosolic Phospholipase A₂α Inhibitors: Discovery and in Vitro and in Vivo Characterization of 4-{3-[5-Chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1<i>H</i>-indol-3-yl]propyl}benzoic Acid, Efipladib

John C. McKew, Katherine L. Lee, Marina W. H. Shen et al. · Journal of Medicinal Chemistry · 2008 · 88 citations

Inhibition of Cytosolic Phospholipase A₂α: Hit to Lead Optimization

John C. McKew, Megan A. Foley, Paresh Thakker et al. · Journal of Medicinal Chemistry · 2005 · 76 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Inhibitory Activity +13

A fluorescence-based assay for fatty acid amide hydrolase compatible with high-throughput screening

Manjunath Ramarao, Elizabeth Murphy, Marina W. H. Shen et al. · Analytical Biochemistry · 2005 · 67 citations

Lipid Analysis, Biochemistry, Bioanalysis +6