Dagmar E. Ehrnhoefer

EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers

Dagmar E. Ehrnhoefer, Jan Bieschke, Annett Boeddrich et al. · Nature Structural & Molecular Biology · 2008 · 1.4K citations

Off-pathway Oligomers, Protein Assembly, G Protein-coupled Receptor +5

EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity

Jan Bieschke, Jenny Russ, Ralf P. Friedrich et al. · Proceedings of the National Academy of Sciences · 2010 · 990 citations · Full text

Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin

Shu‐ichi Okamoto, Mahmoud A. Pouladi, Maria Talantova et al. · Nature Medicine · 2009 · 425 citations · Full text

Synaptic Plasticity, Medicine, Synaptic Transmission +9

Green tea (−)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models

Dagmar E. Ehrnhoefer, Martin L. Duennwald, Phoebe Markovic et al. · Human Molecular Genetics · 2006 · 413 citations · Full text

Hd Flies, Green Tea Polyphenol, Genetics +18

A post-translational modification signature defines changes in soluble tau correlating with oligomerization in early stage Alzheimer’s disease brain

Ebru Ercan-Herbst, J Ehrig, David C. Schöndorf et al. · Acta Neuropathologica Communications · 2019 · 118 citations · Full text