Mahmoud A. Pouladi

A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease

Maria Björkqvist, Edward J. Wild, Jenny Thiele et al. · The Journal of Experimental Medicine · 2008 · 629 citations · Full text

Novel Pathogenic Pathway, Immune Activation Detectable, Immune Activation +22

Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity

Wenjun Song, Jin Chen, Alejandra M. Petrilli et al. · Nature Medicine · 2011 · 536 citations · Full text

Mitophagy, Signal Transduction, Mitochondrial Function +8

Early Increase in Extrasynaptic NMDA Receptor Signaling and Expression Contributes to Phenotype Onset in Huntington's Disease Mice

Austen J. Milnerwood, Clare M. Gladding, Mahmoud A. Pouladi et al. · Neuron · 2010 · 508 citations · Full text

Synaptic Plasticity, Medicine, Genetics +10

Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin

Shu‐ichi Okamoto, Mahmoud A. Pouladi, Maria Talantova et al. · Nature Medicine · 2009 · 425 citations · Full text

Synaptic Plasticity, Medicine, Synaptic Transmission +9

Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function

Kazuyuki Takata, Tatsuya Kozaki, Christopher Lee et al. · Immunity · 2017 · 352 citations · Full text

Macrophage Biology, Induced Pluripotent Stem Cell, Medicine +8