Ralf P. Friedrich

EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity

Jan Bieschke, Jenny Russ, Ralf P. Friedrich et al. · Proceedings of the National Academy of Sciences · 2010 · 1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Small-molecule conversion of toxic oligomers to nontoxic β-sheet–rich amyloid fibrils

Jan Bieschke, Martin Herbst, Thomas Wiglenda et al. · Nature Chemical Biology · 2011 · 442 citations

Life Sciences, Biochemistry, Molecular Biology +15

Mechanism of amyloid plaque formation suggests an intracellular basis of Aβ pathogenicity

Ralf P. Friedrich, Katharina Tepper, Raik Rönicke et al. · Proceedings of the National Academy of Sciences · 2010 · 307 citations · Full text

Life Sciences, Cell Biology, Neuroscience +17

Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Aβ protofibrils

Gernot Habicht, Christian Haupt, Ralf P. Friedrich et al. · Proceedings of the National Academy of Sciences · 2007 · 213 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Transcription factors Sox8 and Sox10 perform non-equivalent roles during oligodendrocyte development despite functional redundancy

C. Claus Stolt, Petra Lommes, Ralf P. Friedrich et al. · Development · 2004 · 200 citations

Life Sciences, Genetics, Neuroscience +10