Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8 <b>+</b> T cells

Luca Gattinoni, Steven E. Finkelstein, Christopher A. Klebanoff, +10

The Journal of Experimental Medicine

Tumor Regression and Autoimmunity after Reversal of a Functionally Tolerant State of Self-reactive CD8+ T Cells

Willem W. Overwijk, Marc R. Theoret, Steven E. Finkelstein, +15

The Journal of Experimental Medicine

Alphavirus-based DNA vaccine breaks immunological tolerance by activating innate antiviral pathways

Wolfgang W. Leitner, Leroy N. Hwang, Michael DeVeer, +6

Nature Medicine

VaccinationVaccine DevelopmentVaccine TargetImmunologyVirology +5

Vaccine-Stimulated, Adoptively Transferred CD8+ T Cells Traffic Indiscriminately and Ubiquitously while Mediating Specific Tumor Destruction

Douglas C. Palmer, Sanjeeve Balasubramaniam, Ken‐ichi Hanada, +10

The Journal of Immunology

T-regulatory CellImmunologyImmunoeditingImmunologic MechanismT Cells +15

Phosphorylation within the amino-terminal acidic domain I of the phosphoprotein of vesicular stomatitis virus is required for transcription but not for replication

Asit K. Pattnaik, Leroy N. Hwang, Tiandao Li, +4

Journal of Virology

Apoptosis is essential for the increased efficacy of alphaviral replicase-based DNA vaccines

Wolfgang W. Leitner, Leroy N. Hwang, Elke S. Bergmann‐Leitner, +3

Vaccine

VaccinationVaccine DevelopmentVaccine ResearchImmunologyTherapeutic Vaccine +7

Polyadenylation of Vesicular Stomatitis Virus mRNA Dictates Efficient Transcription Termination at the Intercistronic Gene Junctions

Leroy N. Hwang, Nathan Englund, Asit K. Pattnaik

Journal of Virology

Type I Interferons are essential for the efficacy of replicase-based DNA vaccines

Wolfgang W. Leitner, Elke S. Bergmann‐Leitner, Leroy N. Hwang, +1

Vaccine

VaccinationVaccine DevelopmentReplicase-based Dna VaccinesNatural SciencesImmunology +7

The<i>In vivo</i>Expansion Rate of Properly Stimulated Transferred CD8+ T Cells Exceeds That of an Aggressively Growing Mouse Tumor

Leroy N. Hwang, Zhiya Yu, Douglas C. Palmer, +1

Cancer Research

Optimal Replication Activity of Vesicular Stomatitis Virus RNA Polymerase Requires Phosphorylation of a Residue(s) at Carboxy-Terminal Domain II of Its Accessory Subunit, Phosphoprotein P

Leroy N. Hwang, Nathan Englund, Tapas Das, +2

Journal of Virology