Concepedia

Alphavirus-based DNA vaccine breaks immunological tolerance by activating innate antiviral pathways

Wolfgang W. Leitner, Leroy N. Hwang, Michael DeVeer, Aimin Zhou, Robert H. Silverman, Bryan Williams, Thomas W. Dubensky, Ying Han, Nicholas P. Restifo

Nature Medicine · 2002 · 269 citations · 37 references

DOI

Concepts

References

37

Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3

Lena Alexopoulou, Agnieszka Czopik Holt, Ruslan Medzhitov et al. · Nature · 2001 · 6.1K citations

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Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs

Matthew L. Albert, Birthe Sauter, Nina Bhardwaj · Nature · 1998 · 2.3K citations

, , +16

Interferon action and apoptosis are defective in mice devoid of 2′,5′‐oligoadenylate‐dependent RNase L

A. Zhou · The EMBO Journal · 1997 · 566 citations · Full text

, , +9

Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B.

Ashutosh Kumar, Jaharul Haque, Judith Lacoste et al. · Proceedings of the National Academy of Sciences · 1994 · 564 citations

, , +17

Expression cloning of 2-5A-dependent RNAase: A uniquely regulated mediator of interferon action

Anna Zhou · Cell · 1993 · 518 citations · Full text

, , +13