Karen R. Romines

Structure−Activity Relationship Studies of Novel Benzophenones Leading to the Discovery of a Potent, Next Generation HIV Nonnucleoside Reverse Transcriptase Inhibitor

Karen R. Romines, George A. Freeman, Lee T. Schaller et al. · Journal of Medicinal Chemistry · 2005 · 167 citations

Direct synthesis of furans by 3 + 2 cycloadditions between rhodium(II) acetate stabilized carbenoids and acetylenes

H.M.L. Davies, Karen R. Romines · Tetrahedron · 1988 · 111 citations

Chemical Engineering, Engineering, Alkene Metathesis +7

Structure-Based Design of HIV Protease Inhibitors:  Sulfonamide-Containing 5,6-Dihydro-4-hydroxy-2-pyrones as Non-Peptidic Inhibitors

Suvit Thaisrivongs, Harvey I. Skulnick, Steve R. Turner et al. · Journal of Medicinal Chemistry · 1996 · 96 citations · Full text

Hiv Protease Inhibitors, Pharmacotherapy, Antiviral Drug +20

Structure-Based Design of Nonpeptidic HIV Protease Inhibitors:  The Sulfonamide-Substituted Cyclooctylpyranones

Harvey I. Skulnick, Paul D. Johnson, Paul A. Aristoff et al. · Journal of Medicinal Chemistry · 1997 · 85 citations · Full text

Combinatorial Chemistry, Antiviral Drug, Chemical Biology +17

Structural Basis for the Improved Drug Resistance Profile of New Generation Benzophenone Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors

Jingshan Ren, Philip P. Chamberlain, Anna Stamp et al. · Journal of Medicinal Chemistry · 2008 · 77 citations

Molecular Biology, Antiviral Drug, Chemical Biology +17