Karen R. Romines - Concepedia

Concepedia

Author

Karen R. Romines

Research Triangle Park Foundation

Also Known As

Karen R Romines, Karen R. Romines

26

Publications

1.1K

Citations

16

H-Index

25

Concepts

All Affiliations

Research Triangle Park Foundation GlaxoSmithKline (United States)Wake Forest University GlaxoSmithKline (United Kingdom)Global Viral

KR

About

Karen R. Romines is an author at Research Triangle Park Foundation specializing in pharmacology, drug discovery, and medicine.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	11	11	583
2	Natural Sciences	6	6	369
3	Biochemistry	5	5	340
4	Biomolecular Engineering	3	3	190
5	Engineering	2	2	145

Karen R. Romines

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17

Publications

1.1K

Citations

16

H-Index

	Year	Citations
Structure−Activity Relationship Studies of Novel Benzophenones Leading to the Discovery of a Potent, Next Generation HIV Nonnucleoside Reverse Transcriptase Inhibitor Karen R. Romines, George A. Freeman, Lee T. Schaller, Journal of Medicinal Chemistry	2005	167
Direct synthesis of furans by 3 + 2 cycloadditions between rhodium(II) acetate stabilized carbenoids and acetylenes H.M.L. Davies, Karen R. Romines Tetrahedron Chemical EngineeringEngineeringAlkene MetathesisOrganic ChemistryCatalysis	1988	111
Structure-Based Design of HIV Protease Inhibitors: Sulfonamide-Containing 5,6-Dihydro-4-hydroxy-2-pyrones as Non-Peptidic Inhibitors Suvit Thaisrivongs, Harvey I. Skulnick, Steve R. Turner, Journal of Medicinal Chemistry Hiv Protease InhibitorsPharmacotherapyAntiviral DrugChemical BiologyDrug Metabolism Research	1996	96
Structure-Based Design of Nonpeptidic HIV Protease Inhibitors: The Sulfonamide-Substituted Cyclooctylpyranones Harvey I. Skulnick, Paul D. Johnson, Paul A. Aristoff, Journal of Medicinal Chemistry Combinatorial ChemistryAntiviral DrugChemical BiologyPharmaceutical ChemistryMedicinal Chemistry	1997	85
Structural Basis for the Improved Drug Resistance Profile of New Generation Benzophenone Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors Jingshan Ren, Philip P. Chamberlain, Anna Stamp, Journal of Medicinal Chemistry Molecular BiologyAntiviral DrugChemical BiologyDrug ResistanceMedicinal Chemistry	2008	77
GSK983: A novel compound with broad-spectrum antiviral activity Kevin Brown, Qin Zhang, Margaret Gartland, Antiviral Research MedicineAntiviral Drug DevelopmentNovel CompoundAntiviral DrugPharmacology	2009	67
Use of Medium-Sized Cycloalkyl Rings To Enhance Secondary Binding: Discovery of a New Class of Human Immunodeficiency Virus (HIV) Protease Inhibitors Karen R. Romines, Keith David Watenpaugh, Paul K. Tomich, Journal of Medicinal Chemistry	1995	65
Novel Benzophenones as Non-nucleoside Reverse Transcriptase Inhibitors of HIV-1 Joseph H. Chan, George A. Freeman, Jeffrey H. Tidwell, Journal of Medicinal Chemistry	2004	64
Antiviral Activity of GW678248, a Novel Benzophenone Nonnucleoside Reverse Transcriptase Inhibitor Robert G. Ferris, Richard Hazen, Grace Roberts, Antimicrobial Agents and Chemotherapy Viral ReplicationImmunologyMolecular BiologyNew GenerationAntiviral Drug	2005	60
Cycloalkylpyranones and Cycloalkyldihydropyrones as HIV Protease Inhibitors: Exploring the Impact of Ring Size on Structure−Activity Relationships Karen R. Romines, Jeanette K. Morris, W. Jeffrey Howe, Journal of Medicinal Chemistry Hiv Protease InhibitorsCell CultureAntiviral DrugChemical BiologyPharmaceutical Chemistry	1996	46

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