Paul A. Aristoff

Tipranavir (PNU-140690):  A Potent, Orally Bioavailable Nonpeptidic HIV Protease Inhibitor of the 5,6-Dihydro-4-hydroxy-2-pyrone Sulfonamide Class

Steve R. Turner, Joseph W. Strohbach, Rubén Tommasi et al. · Journal of Medicinal Chemistry · 1998 · 296 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Nonnucleoside reverse transcriptase inhibitors that potently and specifically block human immunodeficiency virus type 1 replication.

Donna L. Romero, M. Busso, Cheng Keat Tan et al. · Proceedings of the National Academy of Sciences · 1991 · 242 citations

Medicine, Medicinal Chemistry, Pharmacology +16

Steady-state kinetic studies with the non-nucleoside HIV-1 reverse transcriptase inhibitor U-87201E.

Irene W. Althaus, James J. Chou, Andrea J. Gonzales et al. · Journal of Biological Chemistry · 1993 · 164 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Molecular basis for sequence-specific DNA alkylation by CC-1065

Laurence H. Hurley, Chong Soon Lee, J. Patrick McGovren et al. · Biochemistry · 1988 · 144 citations

Life Sciences, Molecular Biology, Dna Repair +6

Novel Riboswitch-Binding Flavin Analog That Protects Mice against Clostridium difficile Infection without Inhibiting Cecal Flora

Ken Blount, Cynthia M. Megyola, Mark S. Plummer et al. · Antimicrobial Agents and Chemotherapy · 2015 · 100 citations · Full text

Medicine, Microbiology, Pharmacology +13