Donna L. Romero

Accurate and Reliable Prediction of Relative Ligand Binding Potency in Prospective Drug Discovery by Way of a Modern Free-Energy Calculation Protocol and Force Field

Lingle Wang, Yujie Wu, Yuqing Deng et al. · Journal of the American Chemical Society · 2015 · 1.3K citations

Drug Target, Engineering, Computational Chemistry +26

Novel 1,5-Diphenylpyrazole Nonnucleoside HIV-1 Reverse Transcriptase Inhibitors with Enhanced Activity versus the Delavirdine-Resistant P236L Mutant:  Lead Identification and SAR of 3- and 4-Substituted Derivatives

Michaël Génin, Carolyn Biles, Barb J. Keiser et al. · Journal of Medicinal Chemistry · 2000 · 375 citations · Full text

Nonnucleoside reverse transcriptase inhibitors that potently and specifically block human immunodeficiency virus type 1 replication.

Donna L. Romero, M. Busso, Cheng Keat Tan et al. · Proceedings of the National Academy of Sciences · 1991 · 242 citations · Full text

Immunology, Molecular Biology, Antiviral Drug +16

The quinoline U-78036 is a potent inhibitor of HIV-1 reverse transcriptase

Irene W. Althaus, Andrea J. Gonzales, James J. Chou et al. · Journal of Biological Chemistry · 1993 · 162 citations · Full text

Viral Replication, Potent Inhibitor, Immunology +19

Kinetic studies with the non-nucleoside HIV-1 reverse transcriptase inhibitor U-88204E

Irene W. Althaus, James J. Chou, Andrea J. Gonzales et al. · Biochemistry · 1993 · 159 citations

Piperazine U-88204e, Molecular Biology, Antiviral Drug +17