Carolyn Biles

Novel 1,5-Diphenylpyrazole Nonnucleoside HIV-1 Reverse Transcriptase Inhibitors with Enhanced Activity versus the Delavirdine-Resistant P236L Mutant:  Lead Identification and SAR of 3- and 4-Substituted Derivatives

Michaël Génin, Carolyn Biles, Barb J. Keiser et al. · Journal of Medicinal Chemistry · 2000 · 378 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

CC-1065(NSC 298223), a potent new antitumor agent. Improved production and isolation, characterization and antitumor activity.

David G. Martin, Carolyn Biles, S. A. Gerpheide et al. · The Journal of Antibiotics · 1981 · 141 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +6

Bis(heteroaryl)piperazine (BHAP) reverse transcriptase inhibitors: structure-activity relationships of novel substituted indole analogs and the identification of 1-[(5-methanesulfonamido-1H-indol-2-yl)carbonyl]-4-[3-[(1-methylethyl)amino]pyridinyl]piperazinemonomethanesulfonate (U-90152S), a second-generation clinical candidate

Donna L. Romero, Raymond A. Morge, Michaël Génin et al. · Journal of Medicinal Chemistry · 1993 · 123 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +8

Primary cultures of hepatocytes on human fibroblasts

George K. Michalopoulos, F.E. Russell, Carolyn Biles · In Vitro Cellular & Developmental Biology - Plant · 1979 · 120 citations

Life Sciences, Biochemistry, Cell Biology +12

Discovery, Synthesis, and Bioactivity of Bis(heteroaryl)piperazines. 1. A Novel Class of Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors

Donna L. Romero, Raymond A. Morge, Carolyn Biles et al. · Journal of Medicinal Chemistry · 1994 · 90 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17