Concepedia

CC-1065(NSC 298223), a potent new antitumor agent. Improved production and isolation, characterization and antitumor activity.

David G. Martin, Carolyn Biles, S. A. Gerpheide, L. J. Haňka, William C. Krueger, J. Patrick McGovren, S. A. MIZSAK, G L Neil, JULIANNA C. STEWART, Jeronimo Visser

The Journal of Antibiotics · 1981 · 141 citations · 6 references

DOIFull text

Open access

Concepts

Abstract

( Received for publication June 15, 1981)CC-1065 (NSC 298223) is a potent new antitumor antibiotic with a unique structure produced by Streptomyces zelensis. Improved production, isolation, and assay methods are described along with physico-chemical properties and antitumor activity.

References

6

CC-1065 (NSC-298223), a new antitumor antibiotic. Production, in vitro biological activity, microbiological assays and taxonomy of the producing microorganism.

L. J. Haňka, A Dietz, S. A. Gerpheide et al. · The Journal of Antibiotics · 1978 · 272 citations · Full text

, , +9

The structure of CC-1065, a potent antitumor agent and its binding to DNA

C. G. CHIDESTER, William C. Krueger, S. A. MIZSAK et al. · Journal of the American Chemical Society · 1981 · 152 citations

, , +7

Structure of CC-1065 (NSC-298223), a new antitumor antibiotic.

David G. Martin, C. G. CHIDESTER, David J. Duchamp et al. · The Journal of Antibiotics · 1980 · 95 citations · Full text

, , +6

CC-1065 (NSC 298223), a novel antitumor agent that interacts strongly with double-stranded DNA.

L. H. Li, David H. Swenson, S. L. F. Schpok et al. · PubMed · 1982 · 87 citations

, , +9

Circular dichrometer calibration by Kramers-Kroenig transform methods

William C. Krueger, Loraine M. Pschigoda · Analytical Chemistry · 1971 · 48 citations

, , +12