Raymond A. Morge

Bis(heteroaryl)piperazine (BHAP) reverse transcriptase inhibitors: structure-activity relationships of novel substituted indole analogs and the identification of 1-[(5-methanesulfonamido-1H-indol-2-yl)carbonyl]-4-[3-[(1-methylethyl)amino]pyridinyl]piperazinemonomethanesulfonate (U-90152S), a second-generation clinical candidate

Donna L. Romero, Raymond A. Morge, Michaël Génin et al. · Journal of Medicinal Chemistry · 1993 · 123 citations · Full text

Altmetric Attention Score, Pharmacotherapy, Indole Analogs +18

Discovery, Synthesis, and Bioactivity of Bis(heteroaryl)piperazines. 1. A Novel Class of Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors

Donna L. Romero, Raymond A. Morge, Carolyn Biles et al. · Journal of Medicinal Chemistry · 1994 · 90 citations

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +13

Targeting Delavirdine/Atevirdine Resistant HIV-1:  Identification of (Alkylamino)piperidine-Containing Bis(heteroaryl)piperazines as Broad Spectrum HIV-1 Reverse Transcriptase Inhibitors

Donna L. Romero, Robert A. Olmsted, Toni J. Poel et al. · Journal of Medicinal Chemistry · 1996 · 57 citations · Full text

(Alkylamino) piperidine bis(heteroaryl)piperizine analogs are potent, broad-spectrum nonnucleoside reverse transcriptase inhibitors of drug-resistant isolates of human immunodeficiency virus type 1 (HIV-1) and select for drug-resistant variants of HIV-1IIIB with reduced replication phenotypes

Robert A. Olmsted, Dea Slade, Laurice A. Kopta et al. · Journal of Virology · 1996 · 37 citations · Full text

Immunology, Molecular Biology, Pharmacotherapy +17

Reaction of 2-(alkylsulfinyl)-, 2-(arylsulfinyl)-, and 2-(aralkylsulfinyl)benzimidazoles with thiols: a convenient synthesis of unsymmetrical disulfides

David R. Graber, Raymond A. Morge, John C. Sih · The Journal of Organic Chemistry · 1987 · 28 citations

Diversity Oriented Synthesis, Engineering, Donut Icon +12