John C. Sih

Omeprazole, a specific inhibitor of gastric (H+-K+)-ATPase, is a H+-activated oxidizing agent of sulfhydryl groups.

Wha Bin Im, John C. Sih, David P. Blakeman et al. · Journal of Biological Chemistry · 1985 · 105 citations · Full text

(<i>S</i>)-(−)-4-[4-[2-(Isochroman-1-yl)ethyl]piperazin-1-yl]benzenesulfonamide, a Selective Dopamine D₄ Antagonist

Ruth E. TenBrink, Carol L. Bergh, J. Neil Duncan et al. · Journal of Medicinal Chemistry · 1996 · 98 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Medicine +12

Practical Asymmetric Synthesis of (<i>S</i>)-4-Ethyl-7,8-dihydro-4-hydroxy-1<i>H</i>-pyrano[3,4-f]indolizine- 3,6,10(4<i>H</i>)-trione, a Key Intermediate for the Synthesis of Irinotecan and Other Camptothecin Analogs

Kevin E. Henegar, Scott W. Ashford, Ted A. Baughman et al. · The Journal of Organic Chemistry · 1997 · 96 citations

Diversity Oriented Synthesis, Natural Product Synthesis, Key Intermediate +14

Total synthesis of prostaglandins. Control of regiospecificity in the alane-epoxide reaction and selective catalytic oxidation of alkynylation products

Josef Fried, John C. Sih · Tetrahedron Letters · 1973 · 85 citations

Biosynthesis, Engineering, Alkene Metathesis +10

Synthesis and Biological Activity of Analogues of the Antidiabetic/Antiobesity Agent 3-Guanidinopropionic Acid:  Discovery of a Novel Aminoguanidinoacetic Acid Antidiabetic Agent

Scott D. Larsen, Mark A. Connell, Michele M. Cudahy et al. · Journal of Medicinal Chemistry · 2001 · 70 citations