Kevin E. Henegar

Practical Asymmetric Synthesis of (<i>S</i>)-4-Ethyl-7,8-dihydro-4-hydroxy-1<i>H</i>-pyrano[3,4-f]indolizine- 3,6,10(4<i>H</i>)-trione, a Key Intermediate for the Synthesis of Irinotecan and Other Camptothecin Analogs

Kevin E. Henegar, Scott W. Ashford, Ted A. Baughman et al. · The Journal of Organic Chemistry · 1997 · 96 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

Utilizing Structures of CYP2D6 and BACE1 Complexes To Reduce Risk of Drug–Drug Interactions with a Novel Series of Centrally Efficacious BACE1 Inhibitors

Michael A. Brodney, Elizabeth M. Beck, Christopher R. Butler et al. · Journal of Medicinal Chemistry · 2015 · 78 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Inside-outside stereoisomerism. II. Synthesis of the carbocyclic ring system of the ingenane diterpenes via the intramolecular dioxolenone photocycloaddition

Jeffrey D. Winkler, Kevin E. Henegar, Paul G. Williard · Journal of the American Chemical Society · 1987 · 59 citations

Natural Sciences, Chemistry, Bioisosterism +6

Process Development for (<i>S,S</i>)-Reboxetine Succinate via a Sharpless Asymmetric Epoxidation

Kevin E. Henegar, Mateusz Cebula · Organic Process Research & Development · 2007 · 55 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

Maximizing Lipophilic Efficiency: The Use of Free-Wilson Analysis in the Design of Inhibitors of Acetyl-CoA Carboxylase

Kevin D. Freeman‐Cook, Paul A. Amor, Scott J. Bader et al. · Journal of Medicinal Chemistry · 2011 · 54 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17