Ruth E. TenBrink

Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with CP-690550 and CMP-6

Jill Chrencik, Akshay Patny, Iris Leung et al. · Journal of Molecular Biology · 2010 · 224 citations

Protein Function, Signal Transduction, Biochemistry +13

Identification of <i>N</i>-{<i>cis</i>-3-[Methyl(7<i>H</i>-pyrrolo[2,3-<i>d</i>]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases

Michael L. Vazquez, Neelu Kaila, Joseph W. Strohbach et al. · Journal of Medicinal Chemistry · 2018 · 160 citations · Full text

Immunodeficiencies, Janus Kinases, Immunology +22

Antagonist, Partial Agonist, and Full Agonist Imidazo[1,5-a]quinoxaline Amides and Carbamates Acting through the GABAA/Benzodiazepine Receptor

Ruth E. TenBrink, Wha Bin Im, Vimala H. Sethy et al. · Journal of Medicinal Chemistry · 1994 · 137 citations · Full text

(<i>S</i>)-(−)-4-[4-[2-(Isochroman-1-yl)ethyl]piperazin-1-yl]benzenesulfonamide, a Selective Dopamine D₄ Antagonist

Ruth E. TenBrink, Carol L. Bergh, J. Neil Duncan et al. · Journal of Medicinal Chemistry · 1996 · 98 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Medicine +12

Pharmacological characterization of U-101387, a dopamine D4 receptor selective antagonist.

Kalpana Merchant, G.S. Gill, David W. Harris et al. · Journal of Pharmacology and Experimental Therapeutics · 1996 · 89 citations · Full text