Akshay Patny

Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with CP-690550 and CMP-6

Jill Chrencik, Akshay Patny, Iris Leung et al. · Journal of Molecular Biology · 2010 · 224 citations

Protein Function, Signal Transduction, Biochemistry +13

Discovery of Clinical Candidate 1-{[(2 <i>S</i> ,3 <i>S</i> ,4 <i>S</i> )-3-Ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide (PF-06650833), a Potent, Selective Inhibitor of Interleukin-1 Receptor Associated Kinase 4 (IRAK4), by Fragment-Based Drug Design

Katherine L. Lee, Catherine M. Ambler, David R. Anderson et al. · Journal of Medicinal Chemistry · 2017 · 138 citations · Full text

Identification of Novel Parasitic Cysteine Protease Inhibitors Using Virtual Screening. 1. The ChemBridge Database

Prashant Desai, Akshay Patny, Yogesh Sabnis et al. · Journal of Medicinal Chemistry · 2004 · 107 citations · Full text

Hit Identification, Biomolecular Structure Prediction, Antiparasitic Agent +19

Mollamides B and C, Cyclic Hexapeptides from the Indonesian Tunicate <i>Didemnum molle</i>

Marwa S. Donia, Bin Wang, Daniel C. Dunbar et al. · Journal of Natural Products · 2008 · 91 citations · Full text

Medicinal Chemistry, Pharmaceutical Chemistry, Biochemistry +12

Identification of Novel Parasitic Cysteine Protease Inhibitors by Use of Virtual Screening. 2. The Available Chemical Directory

Prashant Desai, Akshay Patny, Jiří Gut et al. · Journal of Medicinal Chemistry · 2006 · 78 citations · Full text