George A. Freeman

Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase.

P A Furman, James A. Fyfe, M H St Clair et al. · Proceedings of the National Academy of Sciences · 1986 · 1.3K citations · Full text

Viral Replication, Thymidine Analog, Immunology +18

Structure−Activity Relationship Studies of Novel Benzophenones Leading to the Discovery of a Potent, Next Generation HIV Nonnucleoside Reverse Transcriptase Inhibitor

Karen R. Romines, George A. Freeman, Lee T. Schaller et al. · Journal of Medicinal Chemistry · 2005 · 167 citations

Antibacterial activity and mechanism of action of 3'-azido-3'-deoxythymidine (BW A509U)

Lynn P. Elwell, Robert Ferone, George A. Freeman et al. · Antimicrobial Agents and Chemotherapy · 1987 · 158 citations · Full text

Thymidine Analog, Bioorganic Chemistry, Microbial Pathogens +22

Synthesis and Antiviral Activity of 2‘-Deoxy-4‘-thio Purine Nucleosides

Nanine A. Van Draanen, George A. Freeman, Steven A. Short et al. · Journal of Medicinal Chemistry · 1996 · 70 citations

Medicinal Chemistry, Hbv Replication, Antiviral Activity +13

Novel Benzophenones as Non-nucleoside Reverse Transcriptase Inhibitors of HIV-1

Joseph H. Chan, George A. Freeman, Jeffrey H. Tidwell et al. · Journal of Medicinal Chemistry · 2004 · 64 citations · Full text