Harvey I. Skulnick

Tipranavir (PNU-140690):  A Potent, Orally Bioavailable Nonpeptidic HIV Protease Inhibitor of the 5,6-Dihydro-4-hydroxy-2-pyrone Sulfonamide Class

Steve R. Turner, Joseph W. Strohbach, Rubén Tommasi et al. · Journal of Medicinal Chemistry · 1998 · 293 citations · Full text

Structure-Based Design of HIV Protease Inhibitors:  Sulfonamide-Containing 5,6-Dihydro-4-hydroxy-2-pyrones as Non-Peptidic Inhibitors

Suvit Thaisrivongs, Harvey I. Skulnick, Steve R. Turner et al. · Journal of Medicinal Chemistry · 1996 · 96 citations · Full text

Hiv Protease Inhibitors, Pharmacotherapy, Antiviral Drug +20

Structure-Based Design of Nonpeptidic HIV Protease Inhibitors:  The Sulfonamide-Substituted Cyclooctylpyranones

Harvey I. Skulnick, Paul D. Johnson, Paul A. Aristoff et al. · Journal of Medicinal Chemistry · 1997 · 85 citations · Full text

Combinatorial Chemistry, Antiviral Drug, Chemical Biology +17

General, efficient, one-step synthesis of .beta.-keto esters

Wendell Wierenga, Harvey I. Skulnick · The Journal of Organic Chemistry · 1979 · 83 citations

Altmetrics, Enantioselective Synthesis, Engineering +13

Structure-Based Design of Sulfonamide-Substituted Non-Peptidic HIV Protease Inhibitors

Harvey I. Skulnick, Paul D. Johnson, W. Jeffrey Howe et al. · Journal of Medicinal Chemistry · 1995 · 58 citations · Full text

Medicinal Chemistry, Pharmaceutical Research, Antiviral Compound +15