Middleton B. Floyd

Synthesis and Structure–Activity Relationships of 3-Cyano-4-(phenoxyanilino)quinolines as MEK (MAPKK) Inhibitors

Nan Zhang, Biqi Wu, Dennis Powell et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 48 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +8

Lead identification to generate 3-cyanoquinoline inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment

Lori M. Miller, Scott C. Mayer, Dan M. Berger et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 42 citations

Medicine, Pathology, Lead Identification +10

Benzo[c][2,7]naphthyridines as inhibitors of PDK-1

Kyung‐Hee Kim, Allan Wissner, Middleton B. Floyd et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 27 citations · Full text

Medicinal Chemistry, Medicine, Organic Chemistry +4

4-Anilino-7-alkenylquinoline-3-carbonitriles as potent MEK1 kinase inhibitors

Dan M. Berger, Minu Dutia, Dennis Powell et al. · Bioorganic & Medicinal Chemistry · 2008 · 16 citations · Full text

Medicinal Chemistry, Medicine, Anti-cancer Agent +3