Joanna J. Zheng

Screening and Identification of GSH-Trapped Reactive Metabolites Using Hybrid Triple Quadruple Linear Ion Trap Mass Spectrometry

Joanna J. Zheng, Li Ma, Baomin Xin et al. · Chemical Research in Toxicology · 2007 · 120 citations

Biological Mass Spectrometry, Metabolomic Profiling, Multiple Reaction Monitoring +17

Discovery of Milvexian, a High-Affinity, Orally Bioavailable Inhibitor of Factor XIa in Clinical Studies for Antithrombotic Therapy

Andrew K. Dilger, Kumar B. Pabbisetty, James R. Corte et al. · Journal of Medicinal Chemistry · 2021 · 93 citations · Full text

P2Y6 Receptor Potentiates Pro-Inflammatory Responses in Macrophages and Exhibits Differential Roles in Atherosclerotic Lesion Development

Ricardo Alexandrino Garcia, Mujing Yan, Debra Search et al. · PLoS ONE · 2014 · 89 citations · Full text

Conformationally Constrained <i>ortho-</i>Anilino Diaryl Ureas: Discovery of 1-(2-(1′-Neopentylspiro[indoline-3,4′-piperidine]-1-yl)phenyl)-3-(4-(trifluoromethoxy)phenyl)urea, a Potent, Selective, and Bioavailable P2Y₁ Antagonist

Jennifer X. Qiao, Tammy C. Wang, Réjean Ruel et al. · Journal of Medicinal Chemistry · 2013 · 69 citations · Full text

Thrombosis, Medicinal Chemistry, Biochemistry +13

Discovery of a Parenteral Small Molecule Coagulation Factor XIa Inhibitor Clinical Candidate (BMS-962212)

Donald Pinto, Michael J. Orwat, Leon M. Smith et al. · Journal of Medicinal Chemistry · 2017 · 50 citations · Full text