Debra Search

P2Y6 Receptor Potentiates Pro-Inflammatory Responses in Macrophages and Exhibits Differential Roles in Atherosclerotic Lesion Development

Ricardo Alexandrino Garcia, Mujing Yan, Debra Search et al. · PLoS ONE · 2014 · 90 citations · Full text

Life Sciences, Cell Biology, Pharmacology +17

Selective FPR2 Agonism Promotes a Proresolution Macrophage Phenotype and Improves Cardiac Structure-Function Post Myocardial Infarction

Ricardo Alexandrino Garcia, John A. Lupisella, Bruce R. Ito et al. · JACC Basic to Translational Science · 2021 · 55 citations · Full text

Medicine, Cardiology, Pharmacology +17

Discovery of an Oxybenzylglycine Based Peroxisome Proliferator Activated Receptor α Selective Agonist 2-((3-((2-(4-Chlorophenyl)-5-methyloxazol-4-yl)methoxy)benzyl)(methoxycarbonyl)amino)acetic Acid (BMS-687453)

Jun Li, Lawrence J. Kennedy, Yan Shi et al. · Journal of Medicinal Chemistry · 2010 · 41 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

(3<i>R,</i>5<i>S,E</i>)-7-(4-(4-Fluorophenyl)-6-isopropyl-2-(methyl(1-methyl-1<i>H</i>-1,2,4-triazol-5-yl)amino)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic Acid (BMS-644950): A Rationally Designed Orally Efficacious 3-Hydroxy-3-methylglutaryl Coenzyme-A Reductase Inhibitor with Reduced Myotoxicity Potential

Saleem Ahmad, Cort S. Madsen, Philip D. Stein et al. · Journal of Medicinal Chemistry · 2008 · 36 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Novel Peroxisome Proliferator-Activated Receptor α Agonists Lower Low-Density Lipoprotein and Triglycerides, Raise High-Density Lipoprotein, and Synergistically Increase Cholesterol Excretion with a Liver X Receptor Agonist

Ranjan Mukherjee, Kenneth T. Locke, Bowman Miao et al. · Journal of Pharmacology and Experimental Therapeutics · 2008 · 35 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14