Kenneth T. Locke

The Bioactive Conformation of Human Parathyroid Hormone. Structural Evidence for the Extended Helix Postulate

Stephen M. Condon, Isabelle Morize, Shelley Darnbrough et al. · Journal of the American Chemical Society · 2000 · 44 citations

Parathyroid Disease, Molecular Biology, Conformational Restrictions +23

Ligand and coactivator recruitment preferences of peroxisome proliferator activated receptor α

Ranjan Mukherjee, Shaoxian Sun, Linda D. Santomenna et al. · The Journal of Steroid Biochemistry and Molecular Biology · 2002 · 41 citations

Molecular Physiology, Biochemistry, Medicine +7

Discovery of an Oxybenzylglycine Based Peroxisome Proliferator Activated Receptor α Selective Agonist 2-((3-((2-(4-Chlorophenyl)-5-methyloxazol-4-yl)methoxy)benzyl)(methoxycarbonyl)amino)acetic Acid (BMS-687453)

Jun Li, Lawrence J. Kennedy, Yan Shi et al. · Journal of Medicinal Chemistry · 2010 · 40 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Crystal Structure +14

Discovery of azetidinone acids as conformationally-constrained dual PPARα/γ agonists

Wei Wang, Pratik Devasthale, Dennis Farrelly et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 37 citations · Full text

Molecular Pharmacology, Biochemistry, Medicine +8

Design, synthesis and structure–activity relationships of azole acids as novel, potent dual PPAR α/γ agonists

Hao Zhang, Denis E. Ryono, Pratik Devasthale et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 35 citations · Full text

Biochemistry, Medicine, Natural Sciences +9