Denis E. Ryono - Concepedia

Concepedia

Author

Denis E. Ryono

Bristol-Myers Squibb (United States)

Also Known As

D. E. RYONO, D. Ryono, D.E. Ryono, Denis E Ryono, Denis E. Ryono, Denis Ryono

58

Publications

1.7K

Citations

21

H-Index

38

Concepts

All Affiliations

Bristol-Myers Squibb (United States)Bristol-Myers Squibb (Germany)Bristol-Myers Squibb (Sweden)Karo Pharma (Sweden)Princeton University

DE

About

Denis E. Ryono is an author at Bristol-Myers Squibb (United States) specializing in drug discovery, medicine, and pharmacology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	16	22	1.2K
2	Biochemistry	15	19	1.1K
3	Natural Sciences	13	15	851
4	Engineering	2	2	58
5	Health Sciences	1	1	80

Denis E. Ryono

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33

Publications

1.7K

Citations

21

H-Index

	Year	Citations
Preparation of peptidic α-hydroxy phosphonates a new class of transition state analog renin inhibitors Dinesh V. Patel, Katherine Rielly-Gauvin, Denis E. Ryono Tetrahedron Letters Molecular PharmacologyPeptidic α-Hydroxy PhosphonatesBiochemistryMedicineNew Class	1990	237
Dual Metalloprotease Inhibitors: Mercaptoacetyl-Based Fused Heterocyclic Dipeptide Mimetics as Inhibitors of Angiotensin-Converting Enzyme and Neutral Endopeptidase Jeffrey A. Robl, Chong‐Qing Sun, Jay Stevenson, Journal of Medicinal Chemistry HypertensionChemical BiologyMedicinal ChemistryCompound 1ADual Metalloprotease Inhibitors	1997	198
.alpha.-Hydroxy Phosphinyl-Based Inhibitors of Human Renin Dinesh V. Patel, Katherine Rielly-Gauvin, Denis E. Ryono, Journal of Medicinal Chemistry Pharmaceutical ScienceBioorganic ChemistryPharmacotherapyChemical BiologyPharmaceutical Chemistry	1995	189
Design and Synthesis of <i>N</i>-[(4-Methoxyphenoxy)carbonyl]-<i>N</i>-[[4-[2-(5- methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]methyl]glycine [Muraglitazar/BMS-298585], a Novel Peroxisome Proliferator-Activated Receptor α/γ Dual Agonist with Efficacious Glucose and Lipid-Lowering Activities Pratik Devasthale, Sean Chen, Yoon Jeon, Journal of Medicinal Chemistry	2004	108
Peptidic α-hydroxy phosphinyls C-terminal modification methodology Dinesh V. Patel, Katherine Rielly-Gauvin, Denis E. Ryono Tetrahedron Letters Bioorganic ChemistryBiochemistryNatural SciencesPeptide SynthesisPeptide Science	1990	102
Muraglitazar, a Novel Dual (α/γ) Peroxisome Proliferator–Activated Receptor Activator, Improves Diabetes and Other Metabolic Abnormalities and Preserves β-Cell Function in <i>db/db</i> Mice Thomas Harrity, Dennis Farrelly, Aaron Tieman, Diabetes Ppar Target GenesImmunologyPharmacotherapyMetabolic RemodelingInsulin Signaling	2006	80
Activated ketone based inhibitors of human renin Dinesh V. Patel, Katherine Rielly-Gauvin, Denis E. Ryono, Journal of Medicinal Chemistry	1993	65
Dual Metalloprotease Inhibitors. 6. Incorporation of Bicyclic and Substituted Monocyclic Azepinones as Dipeptide Surrogates in Angiotensin-Converting Enzyme/Neutral Endopeptidase Inhibitors Jeffrey A. Robl, Maria P. Cimarusti, Ligaya M. Simpkins, Journal of Medicinal Chemistry Bicyclic Azepinone 3QPharmaceutical ScienceBioorganic ChemistryPharmacotherapyChemical Biology	1996	60
Thyroid receptor ligands. Part 2: Thyromimetics with improved selectivity for the thyroid hormone receptor beta Jon J. Hangeland, Arthur M. Doweyko, Tamara Dejneka, Bioorganic & Medicinal Chemistry Letters MedicineHormonal ReceptorThyroid DiseaseParathyroid HormoneReceptor (Biochemistry)	2004	52
Angiotensin-converting enzyme inhibitors: importance of the amide carbonyl of mercaptoacyl amino acids for hydrogen bonding to the enzyme Michael E. Condon, Edward W. Petrillo, Denis E. Ryono, Journal of Medicinal Chemistry Bioorganic ChemistryAmide CarbonylChemical BiologyEnzymatic ModificationPharmaceutical Chemistry	1982	51

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