Odalys Gonzalez Paz

Discovery of Raltegravir, a Potent, Selective Orally Bioavailable HIV-Integrase Inhibitor for the Treatment of HIV-AIDS Infection

Vincenzo Summa, Alessia Petrocchi, Fabio Bonelli et al. · Journal of Medicinal Chemistry · 2008 · 634 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

4,5-Dihydroxypyrimidine Carboxamides and <i>N</i>-Alkyl-5-hydroxypyrimidinone Carboxamides Are Potent, Selective HIV Integrase Inhibitors with Good Pharmacokinetic Profiles in Preclinical Species

Vincenzo Summa, Alessia Petrocchi, Victor G. Matassa et al. · Journal of Medicinal Chemistry · 2006 · 100 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +13

Construction of an rtTA2s-m2/ttskid-Based transcription regulatory switch that displays no basal activity, good inducibility, and high responsiveness to doxycycline in mice and Non-Human primates

Stefania Lamartina, Luisa Silvi, Giuseppe Roscilli et al. · Molecular Therapy · 2003 · 85 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +13

Dihydroxypyrimidine-4-carboxamides as Novel Potent and Selective HIV Integrase Inhibitors

Paola Pace, Maria Emilia Di Francesco, Cristina Gardelli et al. · Journal of Medicinal Chemistry · 2007 · 77 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Discovery and Synthesis of HIV Integrase Inhibitors:  Development of Potent and Orally Bioavailable N-Methyl Pyrimidones

Cristina Gardelli, Emanuela Nizi, Ester Muraglia et al. · Journal of Medicinal Chemistry · 2007 · 67 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17