Cristina Gardelli

Discovery of Raltegravir, a Potent, Selective Orally Bioavailable HIV-Integrase Inhibitor for the Treatment of HIV-AIDS Infection

Vincenzo Summa, Alessia Petrocchi, Fabio Bonelli et al. · Journal of Medicinal Chemistry · 2008 · 624 citations · Full text

Antiviral Drug, Medicinal Chemistry, Antiviral Drug Development +16

4,5-Dihydroxypyrimidine Carboxamides and <i>N</i>-Alkyl-5-hydroxypyrimidinone Carboxamides Are Potent, Selective HIV Integrase Inhibitors with Good Pharmacokinetic Profiles in Preclinical Species

Vincenzo Summa, Alessia Petrocchi, Victor G. Matassa et al. · Journal of Medicinal Chemistry · 2006 · 99 citations · Full text

Bioorganic Chemistry, Pharmacotherapy, Antiviral Drug +17

Enantioselective Total Synthesis of the Antitumor Macrolide Rhizoxin D

Jennifer Lafontaine, David P. Provencal, Cristina Gardelli et al. · The Journal of Organic Chemistry · 2003 · 88 citations

Dihydroxypyrimidine-4-carboxamides as Novel Potent and Selective HIV Integrase Inhibitors

Paola Pace, Maria Emilia Di Francesco, Cristina Gardelli et al. · Journal of Medicinal Chemistry · 2007 · 76 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Bioorganic Chemistry +15

Discovery and Synthesis of HIV Integrase Inhibitors:  Development of Potent and Orally Bioavailable N-Methyl Pyrimidones

Cristina Gardelli, Emanuela Nizi, Ester Muraglia et al. · Journal of Medicinal Chemistry · 2007 · 67 citations · Full text

Medicinal Chemistry, Interesting Compounds, Biochemistry +15