Mai Uesugi

Splicing factor SF3b as a target of the antitumor natural product pladienolide

Yoshihiko Kotake, Koji Sagane, Takashi Owa et al. · Nature Chemical Biology · 2007 · 659 citations · Full text

Medicine, Molecular Biology, Oncology +9

Selective Inhibition of EZH2 by EPZ-6438 Leads to Potent Antitumor Activity in <i>EZH2</i> -Mutant Non-Hodgkin Lymphoma

Sarah K. Knutson, Satoshi Kawano, Yukinori Minoshima et al. · Molecular Cancer Therapeutics · 2014 · 522 citations

Medicine, Oncology, Pharmacology +14

Selective degradation of splicing factor CAPERα by anticancer sulfonamides

Taisuke Uehara, Yukinori Minoshima, Koji Sagane et al. · Nature Chemical Biology · 2017 · 379 citations

Medicine, Molecular Biology, Pharmacology +14

Eribulin mesylate reduces tumor microenvironment abnormality by vascular remodeling in preclinical human breast cancer models

Yasuhiro Funahashi, Kiyoshi Okamoto, Yusuke Adachi et al. · Cancer Science · 2014 · 278 citations · Full text

Medicine, Oncology, Pharmacology +17

Human HRD1 protects against ER stress‐induced apoptosis through ER‐associated degradation¹

Masayuki Kaneko, Masataro Ishiguro, Yoshifumi Niinuma et al. · FEBS Letters · 2002 · 220 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17