Jeanne M. Rumsey

MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A

Agostinho G. Rocha, Antonietta Franco, Andrzej M. Krezel et al. · Science · 2018 · 252 citations

Life Sciences, Neurobiology, Neuroscience +17

Integrated Bottom-Up and Top-Down Proteomics of Patient-Derived Breast Tumor Xenografts

Ioanna Ntai, Richard D. LeDuc, Ryan T. Fellers et al. · Molecular & Cellular Proteomics · 2015 · 83 citations · Full text

Life Sciences, Biochemistry, Oncology +17

Inhibition of Cytochrome P450 3A4 by a Pyrimidineimidazole:  Evidence for Complex Heme Interactions

J. Matthew Hutzler, Roger J. Melton, Jeanne M. Rumsey et al. · Chemical Research in Toxicology · 2006 · 38 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Discovery of novel spirocyclic inhibitors of fatty acid amide hydrolase (FAAH). Part 2. Discovery of 7-azaspiro[3.5]nonane urea PF-04862853, an orally efficacious inhibitor of fatty acid amide hydrolase (FAAH) for pain

Marvin J. Meyers, Scott A. Long, Matthew J. Pelc et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 31 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Investigation of aminopyridiopyrazinones as PDE5 inhibitors: Evaluation of modifications to the central ring system

Robert Hughes, John K. Walker, Jerry W. Cubbage et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 19 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8