Matthew J. Pelc

A Novel Autotaxin Inhibitor Reduces Lysophosphatidic Acid Levels in Plasma and the Site of Inflammation

James K. Gierse, Atli Thorarensen, Konstantine Beltey et al. · Journal of Pharmacology and Experimental Therapeutics · 2010 · 226 citations

An Approach to the Imine Ring System of Pinnatoxins

Matthew J. Pelc, Armen Zakarian · Organic Letters · 2005 · 49 citations

Development of the Enabling Route for Glecaprevir via Ring-Closing Metathesis

Russell D. Cink, K. A. LUKIN, Richard D. Bishop et al. · Organic Process Research & Development · 2019 · 37 citations

Medicinal Chemistry, Biochemistry, Ring-closing Metathesis +15

Structure-based drug design enables conversion of a DFG-in binding CSF-1R kinase inhibitor to a DFG-out binding mode

Marvin J. Meyers, Matthew J. Pelc, Satwik Kamtekar et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 35 citations · Full text

Drug Target, Signal Transduction, Medicine +9

Discovery of 3-Cyano- <i>N</i> -(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 <i>H</i> -pyrrolo[2,3- <i>b</i> ]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonist

Mark E. Schnute, Mattias Wennerstål, Jennifer Alley et al. · Journal of Medicinal Chemistry · 2018 · 32 citations · Full text