J. Matthew Hutzler - Concepedia

Author

J. Matthew Hutzler

Also Known As

Hutzler, J. Matthew, J HUTZLER, J M Hutzler, J Matthew Hutzler, J. Matthew Hutzler, J.Matthew Hutzler, James M. Hutzler, James Matthew Hutzler

Publications

1.9K

Citations

H-Index

Concepts

All Affiliations

Pfizer (United States)West Virginia University Boehringer Ingelheim (United States)Q2 Solutions (United States)University of Pittsburgh

About

J. Matthew Hutzler is an author at Pfizer (United States) specializing in medicine, pharmacology, and biochemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	9	9	377
2	Biochemistry	9	9	379
3	Natural Sciences	4	4	115
4	Metabolism	3	3	203
5	Chemical Biology	1	1	24

J. Matthew Hutzler

Publications

1.4K

Citations

H-Index

Page 1

	Year	Citations
INDUCTION AND INHIBITION OF CYTOCHROMES P450 BY THE ST. JOHN’S WORT CONSTITUENT HYPERFORIN IN HUMAN HEPATOCYTE CULTURES Bernard J. Komoroski, Shimin Zhang, Hongbo Cai, Drug Metabolism and Disposition	2004	180
Dapsone activation of CYP2C9-mediated metabolism: evidence for activation of multiple substrates and a two-site model. J. Matthew Hutzler, M J Hauer, T. S. Tracy PubMed Pharmaceutical ScienceMultiple SubstratesDapsone Hydroxylamine FormationExperimental PharmacologyPharmaceutical Chemistry	2001	105
IN VITRO METABOLISM OF CLINDAMYCIN IN HUMAN LIVER AND INTESTINAL MICROSOMES Michael A. Wynalda, J. Matthew Hutzler, Michael D. Koets, Drug Metabolism and Disposition	2003	101
Is 1-Aminobenzotriazole an Appropriate in Vitro Tool as a Nonspecific Cytochrome P450 Inactivator? Collette Linder, Nicole Renaud, J. Matthew Hutzler Drug Metabolism and Disposition	2008	88
Polymorphic Variants (CYP2C93 and CYP2C95) and the F114L Active Site Mutation of CYP2C9: Effect on Atypical Kinetic Metabolism Profiles Timothy S. Tracy, J. Matthew Hutzler, Robert L. Haining, Drug Metabolism and Disposition	2002	81
Characterization of Aldehyde Oxidase Enzyme Activity in Cryopreserved Human Hepatocytes J. Matthew Hutzler, Young-Sun Yang, Daniel Albaugh, Drug Metabolism and Disposition	2011	77
Visible Spectra of Type II Cytochrome P450-Drug Complexes: Evidence that “Incomplete” Heme Coordination Is Common Charles W. Locuson, J. Matthew Hutzler, Timothy S. Tracy Drug Metabolism and Disposition	2007	76
Activation of cytochrome P450 2C9-mediated metabolism: mechanistic evidence in support of kinetic observations J. Matthew Hutzler, Larry C. Wienkers, Jan L. Wahlstrom, Archives of Biochemistry and Biophysics Energy MetabolismBiochemistryMedicineMetabolic ControlMechanistic Evidence	2003	70
Inhibition of Cytochrome P450 2D6: Structure−Activity Studies Using a Series of Quinidine and Quinine Analogues J. Matthew Hutzler, Gregory S. Walker, Larry C. Wienkers Chemical Research in Toxicology	2003	53
Activation of CYP2C9-Mediated Metabolism by a Series of Dapsone Analogs: Kinetics and Structural Requirements J. Matthew Hutzler, Dhanashri Kolwankar, Matthew A. Hummel, Drug Metabolism and Disposition	2002	49

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