Concepedia

IN VITRO METABOLISM OF CLINDAMYCIN IN HUMAN LIVER AND INTESTINAL MICROSOMES

Michael A. Wynalda, J. Matthew Hutzler, Michael D. Koets, Terry Podoll, Larry C. Wienkers

Drug Metabolism and Disposition · 2003 · 102 citations · 37 references

DOI

Concepts

References

37

Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.

Deborah J. Newton, R W Wang, Anthony Y.H. Lu · Drug Metabolism and Disposition · 1995 · 606 citations

, , +17

Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes.

Gondi Kumar, A. David Rodrigues, Alex Buko et al. · Journal of Pharmacology and Experimental Therapeutics · 1996 · 352 citations

, , +17

Prediction of hepatic extraction ratio from in vitro measurement of intrinsic clearance.

A Rane, G. Wilkinson, David G. Shand · Journal of Pharmacology and Experimental Therapeutics · 1977 · 328 citations

, , +17

Steroid hormone hydroxylase specificities of eleven cDNA-expressed human cytochrome P450s

David J. Waxman, D P Lapenson, Toshifumi Aoyama et al. · Archives of Biochemistry and Biophysics · 1991 · 324 citations

, , +14

Oxidation of quinidine by human liver cytochrome P-450.

F. Peter Guengerich, Dieter Müller‐Enoch, Ian A. Blair · Molecular Pharmacology · 1986 · 306 citations

, , +16