Concepedia

Fmo Isoforms

FMO Isoforms is a collective construct referring to a class of genetically distinct yet functionally related enzymes within the flavin-containing monooxygenase family that catalyze the NADPH-dependent oxygenation of heteroatom-containing compounds, distinguished by their unique tissue distribution, substrate specificity, and molecular regulation.

127

Publications

10.2K

Citations

492

Authors

173

Institutions

Publications per year

2017–2026

9

Variants

Flavin-containing Monooxygenase Isoforms

Parents

Publications

127

The Obesity-Associated <i>FTO</i> Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase

Thomas Gerken, Christophe A. Girard, Yi‐Chun Loraine Tung et al. · Science · 2007 · 1.5K citations · Full text

, , +9

Molecular cloning and expression of inducible nitric oxide synthase from human hepatocytes.

David A. Geller, Charles J. Lowenstein, Richard A. Shapiro et al. · Proceedings of the National Academy of Sciences · 1993 · 833 citations

, , +14

Crystal structure of the FTO protein reveals basis for its substrate specificity

Zhifu Han, Tianhui Niu, Junbiao Chang et al. · Nature · 2010 · 422 citations

, , +16

Loss-of-Function Mutation in the Dioxygenase-Encoding FTO Gene Causes Severe Growth Retardation and Multiple Malformations

Sarah Boissel, Orit Reish, Karine Proulx et al. · The American Journal of Human Genetics · 2009 · 401 citations · Full text

, , +11

Flavin-containing monooxygenase 3 as a potential player in diabetes-associated atherosclerosis

Ji Miao, Alisha V. Ling, Praveen V. Manthena et al. · Nature Communications · 2015 · 370 citations · Full text

, , +15

1–5 of 127

Authors

492

  1. RN
    Ronald N. Hines

    Medical College of Wisconsin, United States

    15 publications · 872 citations

    14

    h-index

  2. SK
    Sharon K. Krueger

    Oregon State University, United States

    11 publications · 382 citations

    11

    h-index

  3. HY
    Hiroshi Yamazaki

    Showa Pharmaceutical University, Japan

    9 publications · 214 citations

    9

    h-index

  4. DE
    David E. Williams

    University of British Columbia, Canada

    9 publications · 363 citations

    9

    h-index

  5. EA
    Elizabeth A. Shephard

    University College London, United Kingdom

    8 publications · 818 citations

    8

    h-index

1–5 of 492

Institutions

173

  1. Oregon State University

    Corvallis, United States

    12 h-index

    42 publications

    1.2K citations

  2. National Institute of Environmental Health Sciences

    Durham, United States

    12 h-index

    34 publications

    2.3K citations

  3. North Carolina State University

    Raleigh, United States

    10 h-index

    39 publications

    1.8K citations

  4. University College London

    London, United Kingdom

    10 h-index

    16 publications

    1.8K citations

  5. Medical College of Wisconsin

    Milwaukee, United States

    8 h-index

    16 publications

    1.3K citations

  6. Queen Mary University of London

    London, United Kingdom

    8 h-index

    16 publications

    2.1K citations

  7. Showa Pharmaceutical University

    Tokyo, Japan

    8 h-index

    32 publications

    686 citations

  8. University of Washington

    Seattle, United States

    7 h-index

    22 publications

    3.1K citations

1–8 of 173

Venues

  1. Drug Metabolism and Disposition

    13 publications · 747 citations

    12

    h-index

  2. Archives of Biochemistry and Biophysics

    ABB · 7 publications · 323 citations

    7

    h-index

  3. Molecular Genetics and Metabolism

    6 publications · 374 citations

    6

    h-index

  4. Drug Metabolism and Pharmacokinetics

    DMPK · 5 publications · 93 citations

    5

    h-index

  5. Molecular Pharmacology

    5 publications · 211 citations

    5

    h-index

1–5