Concepedia

Flavin-containing Monooxygenases

Flavin-Containing Monooxygenases is a family of NADPH-dependent monooxygenase enzymes that catalyze the oxygenation of soft nucleophilic heteroatoms in drugs and xenobiotics, distinguished by their reliance on a flavin adenine dinucleotide (FAD) cofactor for catalytic activity.

1.2K

Publications

66.3K

Citations

4.2K

Authors

1K

Institutions

Publications per year

2017–2026

182

Variants

Fmos

Parents

Children

Publications

1.2K

The phenazine pyocyanin is a terminal signalling factor in the quorum sensing network of <i>Pseudomonas aeruginosa</i>

Lars E. P. Dietrich, Alexa Price‐Whelan, Ashley Petersen et al. · Molecular Microbiology · 2006 · 724 citations · Full text

, , +17

Mammalian Microsomal Cytochrome P450 Monooxygenase

Pamela A. Williams, José Cosme, Vandana Sridhar et al. · Molecular Cell · 2000 · 694 citations · Full text

, , +9

Flavin Monooxygenase-Generated N-Hydroxypipecolic Acid Is a Critical Element of Plant Systemic Immunity

Michael Hartmann, Tatyana Zeier, Friederike Bernsdorff et al. · Cell · 2018 · 423 citations · Full text

, , +16

The TMAO-Generating Enzyme Flavin Monooxygenase 3 Is a Central Regulator of Cholesterol Balance

Manya Warrier, Diana M. Shih, Amy Burrows et al. · Cell Reports · 2015 · 416 citations · Full text

, , +17

Tryptophan 7-Halogenase (PrnA) Structure Suggests a Mechanism for Regioselective Chlorination

Changjiang Dong, Silvana Flecks, S. Unversucht et al. · Science · 2005 · 397 citations

, , +17

1–5 of 1.2K

Authors

4.2K

  1. MW
    Marco W. Fraaije

    University of Groningen, Netherlands

    33 publications · 2.3K citations

    27

    h-index

  2. JR
    John R. Cashman

    Human BioMolecular Research Institute, United States

    39 publications · 1.9K citations

    26

    h-index

  3. EH
    Ernest Hodgson

    North Carolina State University, United States

    26 publications · 1.5K citations

    22

    h-index

  4. EA
    Elizabeth A. Shephard

    University College London, United Kingdom

    24 publications · 1.7K citations

    22

    h-index

  5. IP
    Ian Phillips

    St Thomas' Hospital, United Kingdom

    24 publications · 1.7K citations

    22

    h-index

1–5 of 4.2K

Institutions

1K

  1. University of Groningen

    Groningen, The Netherlands

    28 h-index

    109 publications

    7.4K citations

  2. University of Michigan

    Ann Arbor, United States

    27 h-index

    107 publications

    7.3K citations

  3. Oregon State University

    Corvallis, United States

    24 h-index

    89 publications

    3.6K citations

  4. University College London

    London, United Kingdom

    23 h-index

    79 publications

    5.5K citations

  5. North Carolina State University

    Raleigh, United States

    21 h-index

    93 publications

    4.7K citations

  6. Queen Mary University of London

    London, United Kingdom

    21 h-index

    65 publications

    4.6K citations

  7. National Institute of Environmental Health Sciences

    Durham, United States

    21 h-index

    61 publications

    4.6K citations

  8. Centre National de la Recherche Scientifique

    Paris, France

    19 h-index

    61 publications

    2.5K citations

1–8 of 1K

Venues

  1. Journal of Biological Chemistry

    JBC · 77 publications · 5.4K citations

    45

    h-index

  2. Biochemistry

    76 publications · 4.3K citations

    37

    h-index

  3. Journal of the American Chemical Society

    JACS · 54 publications · 3.7K citations

    34

    h-index

  4. Archives of Biochemistry and Biophysics

    ABB · 50 publications · 3K citations

    32

    h-index

  5. Drug Metabolism and Disposition

    57 publications · 2.6K citations

    31

    h-index

1–5